Synthesis and Characterization of some 2,3-dihydroquinozoline and evaluation of their biological activity

Abstract

This work included the synthesis of azo dye (A1) by the reaction of diazonium salt to benzidine with salicyldehyde at (0-5) oC and synthesis of schiff base (A2-A6) through reaction substituted aromatic amine with aldehyde group in azo compound (A1) in ethanol compounds (A2-A6) and 2,3-dihydroquinozoline derivatives prepared by reaction schiff base with anthranilic acid in ethanol compounds (A7-A11), and characterization by using spectroscopic techniques Uv/Vis, FT-IR, C.H.N. and H1-NMR of some the prepared compounds using DMSO-d6 as a solvent, in addition to melting point and determination a purity of TLC, This work consisted a study of biological activity for some prepared compounds against four types of pathogenic bacteria to detect their resistance to anti biotic, drugs.

Green Synthesis of Silver Nanoparticles and Testing its Effectiveness in Inhibiting E. coli, Staphylococcus Aureus Isolated from Urinary Tract Infections of Pregnant Women

“…Two further peaks at 3.00 and 3.20 keV, respectively, were also associated with silver (Ag), while a prominent peak at 1.44 keV showed the presence of silver (Au). Our findings concurred with those of Okaiyeto et al, 2019 who discovered that silver and chloride were present in AgNPs prepared from an aqueous leaf extract of Oedera genistifolia [32]. As per an earlier study [33], a number of components found in the EDX analysis, including Si, Au, and Cl, act as capping agents for the biogenic AgNPs as a whole.…”