Abstract:The synthetic techniques, for the synthesis of Metal oxide nanoparticles involve toxic solvents, high pressure, high-energy and high temperature which may be efficient but not eco-friendly. The synthetic techniques for metal oxide nanoparticles using plants, has several advantages over the chemical synthesis such as cost effectiveness, simplicity as well as compatibility for medical applications. In this part of the study we are using the cynodon dactylon leaf extracts to synthesize titanium dioxide nanopartic… Show more
“…Its relevance in nano drugs development has opened a new era in emerging medicine (Fig. 1 ) (Mohammadinejad et al 2015 ; Hano and Abbasi 2022 ). Fig.…”
Section: An Overview Of the Methods For Preparation Of Plant-derived ...mentioning
confidence: 99%
“…Nanoparticles with negative zeta potential possess higher cellular uptake than positive ones. The lower the negative charge of nanoparticles, the easier the passage into the cell to achieve better interaction with the cellular membranes (Mohammadinejad et al 2015 ; Hanna and Saad 2020 ; Hano and Abbasi 2022 ). This gives nano-particles the advantage in pathogenic microbes and cancer cell studies.…”
Section: An Overview Of the Methods For Preparation Of Plant-derived ...mentioning
Plant-derived nanomaterials (PDNM) have gained significant attention recently due to their potential pharmacological applications against pathogenic microbes, antimicrobial resistance (AMR), and certain metabolic diseases. This review introduces the concept of PDNMs and their unique properties, including their small size, high surface area, and ability to penetrate biological barriers. Besides various methods for synthesizing PDNMs, such as green synthesis techniques that utilize plant extracts and natural compounds, the advantages of using plant-derived materials, such as their biocompatibility, biodegradability, and low toxicity, were elucidated. In addition, it examines the recent and emerging trends in nanomaterials derived from plant approaches to combat antimicrobial resistance and metabolic diseases. The sizes of nanomaterials and their surface areas are vital as they play essential roles in the interactions and relationships between these materials and the biological components or organization. We critically analyze the biomedical applications of nanoparticles which include antibacterial composites for implantable devices and nanosystems to combat antimicrobial resistance, enhance antibiotic delivery, and improve microbial diagnostic/detection systemsIn addition, plant extracts can potentially interfere with metabolic syndrome pathways; hence most nano-formulations can reduce chronic inflammation, insulin resistance, oxidative stress, lipid profile, and antimicrobial resistance. As a result, these innovative plant-based nanosystems may be a promising contender for various pharmacological applications.
“…Its relevance in nano drugs development has opened a new era in emerging medicine (Fig. 1 ) (Mohammadinejad et al 2015 ; Hano and Abbasi 2022 ). Fig.…”
Section: An Overview Of the Methods For Preparation Of Plant-derived ...mentioning
confidence: 99%
“…Nanoparticles with negative zeta potential possess higher cellular uptake than positive ones. The lower the negative charge of nanoparticles, the easier the passage into the cell to achieve better interaction with the cellular membranes (Mohammadinejad et al 2015 ; Hanna and Saad 2020 ; Hano and Abbasi 2022 ). This gives nano-particles the advantage in pathogenic microbes and cancer cell studies.…”
Section: An Overview Of the Methods For Preparation Of Plant-derived ...mentioning
Plant-derived nanomaterials (PDNM) have gained significant attention recently due to their potential pharmacological applications against pathogenic microbes, antimicrobial resistance (AMR), and certain metabolic diseases. This review introduces the concept of PDNMs and their unique properties, including their small size, high surface area, and ability to penetrate biological barriers. Besides various methods for synthesizing PDNMs, such as green synthesis techniques that utilize plant extracts and natural compounds, the advantages of using plant-derived materials, such as their biocompatibility, biodegradability, and low toxicity, were elucidated. In addition, it examines the recent and emerging trends in nanomaterials derived from plant approaches to combat antimicrobial resistance and metabolic diseases. The sizes of nanomaterials and their surface areas are vital as they play essential roles in the interactions and relationships between these materials and the biological components or organization. We critically analyze the biomedical applications of nanoparticles which include antibacterial composites for implantable devices and nanosystems to combat antimicrobial resistance, enhance antibiotic delivery, and improve microbial diagnostic/detection systemsIn addition, plant extracts can potentially interfere with metabolic syndrome pathways; hence most nano-formulations can reduce chronic inflammation, insulin resistance, oxidative stress, lipid profile, and antimicrobial resistance. As a result, these innovative plant-based nanosystems may be a promising contender for various pharmacological applications.
“…NMs have shown better anticancer potential than chemical-methodsynthesized NMs against a lung cancer cell line (A549) at a minimal concentration of 50 μg/ml (Hariharan et al, 2017). Similarly, biogenic magnesium oxide and tin oxide NMs have exhibited anticancer potential against MCF-7 cells (Kgosiemang et al, 2020;, and Rhus coriaria-based green silver NMs have been successfully tested for the inhibition of the breast cancer cell line MCF-7 (Kubatka et al, 2021).…”
Nanotechnology has attracted the attention of researchers from different scientific fields because of the escalated properties of nanomaterials (NMs) compared with the properties of macromolecules. NMs can be prepared through different approaches involving physical and chemical methods. The development of NMs through plantbased green chemistry approaches is more advantageous than other methods from the perspectives of environmental safety, animal, and human health. The biomolecules and metabolites of plants act as reducing and capping agents for the synthesis of metallic green NMs. Plant-based synthesis is a preferred approach as it is not only cost-effective, easy, safe, clean, and eco-friendly but also provides pure NMs in high yield. Since NMs have antimicrobial and antioxidant potential, green NMs synthesized from plants can be used for a variety of biomedical and environmental remediation applications. Past studies have focused mainly on the overall biogenic synthesis of individual or combinations of metallic NMs and their oxides from different biological sources, including microorganisms and biomolecules.Moreover, from the viewpoint of biomedical applications, the literature is mainly focusing on synthetic NMs. Herein, we discuss the extraction of green molecules and recent developments in the synthesis of different plant-based metallic NMs, including silver, gold, platinum, palladium, copper, zinc, iron, and carbon. Apart from the biomedical applications of metallic NMs, including antimicrobial, anticancer, diagnostic, drug delivery, tissue engineering, and regenerative medicine applications, their environmental remediation potential is also discussed. Furthermore, safety concerns and safety regulations pertaining to green NMs are also discussed.
“…The most interesting and beneficial plant extracts used for the synthesis of TiO2 nanoparticles are mentioned in this section. Agar well-diffusion method TiO2 NPs exhibited anti-microbial activity against the growth of E.coli [98] Morinda citrifolia (Indian Mulberry or Noni Tree) has a rich medicinal history in India. The fruit of this plant has been profoundly found in many parts of ancient medicinal texts of Ayurveda and Siddha.…”
The broad reception for nanotechnology is due to their appreciable size and versatile applications in the interdisciplinary areas. In this modern era one of the major problems is microorganisms possessing antibiotic resistance, nanoparticles (NPs) are a lucrative option to solve this. In materials science, “green synthesis” has gained extensive attention as a reliable, sustainable, and eco-friendly protocol for synthesizing a wide range of materials, especially metals, and metal oxides nanomaterials, hybrid materials and bioinspired materials. As such, green synthesis is regarded as an important tool to reduce the destructive effects associated with the traditional methods for synthesis of nanoparticles commonly utilized in laboratory and industry. Bio-inspired NPs held edges over conventionally synthesized nanoparticles due to their low cost, easy synthesis and low toxicity. This chapter elaborates the developments on the biosynthesis of NPs using natural extracts with particular emphasis on their application as microbiocidal agents. This chapter has very specifically dealt with coinage metals such as Cu, Ag, Au due to their significance of antimicrobial activities. Succeeding, reported the developments in the synthetic methodologies of metal-oxide (Titanium dioxide, TiO2) nanoparticles using novel plant extracts with high medicinal value and their corresponding ability to degrade bacterial pathogens through advanced oxidation process (AOPs) based on heterogeneous photocatalysis.
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