Synthesis and crystal structure of imidazole containing amide as a turn on fluorescent probe for nickel ion in aqueous media. An experimental and theoretical investigation

Water Soluble Mixed Ligand Complexes Spectral, antioxidant, antimicrobial and DNA interaction studies

“…The synthesized mixed ligand complexes were soluble in water, methanol, ethanol, CHCl 3 and DMSO. The analytical data and physical properties of the ligand (HL) and complexes (1)(2)(3)(4)(5) due to nitrogen atom is taking part in complexation [23,24]. The absence of singlet peak at the rage of 13 ppm was noted that the complex (5) indicates the loss of the-OH proton due to complexation [25] and there is no appreciable change in other signals in the complex (5).…”

“…The magnetic moment of the complex (2) was observed at 4.82 BM which was within the range 4.7-5.2 BM for octahedral geometry [38,39]. The electronic spectrum of complex (4) showed three bands at 926 nm (10799 cm -1 ), 553 nm (18083 cm -1 ) and 346 nm (28901cm -1 ) corresponding to the transitions 3 A 2g (F)→ 3 T 2g (F), 3 A 2g (F)→ 3 T 1g (F) and 3 A 2g (F)→ 3 T 1g (P). The magnetic moment of the complex (4) was observed at 3.13 BM which was within the range 2.5-3.5 BM for octahedral Ni(II) complexes [40].…”

“…Antimicrobial activities of the ligand (HL) and complexes (1)(2)(3)(4)(5) were screened in vitro against the selected pathogenic bacterial strains and fungi species by the disc diffusion method [17].…”

“…(∆γ a-≥ 200 cm -1 ) [31]. The far IR spectra of the complexes (1)(2)(3)(4)(5) show medium bands in the region 471-462 cm -1 and 516-498 cm -1 corresponding to ν M-N and ν M-O vibrations respectively [32] and other absorption bands were no appreciable change in the ligand (HL) and metal complexes (1-5).…”

“…Schiff base complexes of transition metal have played a prominent role in the development of coordination chemistry. Over recent years a huge number of mixed ligand transition metal(II) complexes having N, O and S donor binding sites have been found to play a vital role in biological systems, clinical, medicinal, agricultural, industrial, analytical and therapeutic applications [1][2][3]. Heterocyclic bases like morpholine, pyrimidine derivative complexes have been extensively studied because of their potential antimicrobial and anticancer activities [4,5] and they are exhibited unusual electronic properties, diverse chemical reactivity and peculiar structure which result in non-covalent interactions with DNA [6].…”