Synthesis and Crystal Structure of a New Schiff Base 4-[(2-hydroxy-benzylidene)-amino]-N-(5-methyl-isoxazol-3-yl)-benzenesulfonamide

4-(Benzylideneamino)benzenesulfonamide

“…For our ongoing studies on the synthesis, structures and biological activity of organometallic Cp*Ru(II) arene complexes Loughrey et al (2008Loughrey et al ( , 2009. For related structures, see Chumakov et al (2006); Subashini et al (2009). Data collection: CrysAlis CCD (Oxford Diffraction, 2007); cell refinement: CrysAlis RED (Oxford Diffraction, 2007); data reduction: CrysAlis RED; program(s) used to solve structure: SIR97 (Altomare et al, 1999); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008); molecular graphics: ORTEP-3 for Windows (Farrugia, 1997); software used to prepare material for publication: PLATON (Spek, 2009).…”

“…this class of compound (Chumakov et al, 2006;Subashini et al, 2009). The -CH=N-azomethine group is rotated slightly out of the plane of the benzaldehyde benzene ring with the torsion angle C43-C42-C41-N4 = 8.1 (3)°.…”

4-[(2-Hydroxybenzylidene)amino]-N-(5-methylisoxazol-3-yl)benzenesulfonamide: a monoclinic polymorph

“…The title compound, C 17 H 15 N 3 O 4 S, is a monoclinic polymorph with space group P2 1 /c of the previously reported triclinic form in P1 [Subashini et al (2009). J.…”

4-[(2-Hydroxy-5-nitrobenzylidene)amino]benzenesulfonamide

“…Schiff bases derived from sulfanilamide exhibit various pharmacological activities including antibacterial, antifungal, antiviral, antimicrobial, anticonvulsant, antitumor, antiulcer, anti-neoplastic, and anti-inflammatory properties as well as acting as enzymatic inhibitors (Wang et al, 2010, Sharaby, 2007, Kremer et al, 2006, Chumakov et al, 2006, Aziz-ur-Rehman et al, 2010, Subashini et al, 2009, Loughrey et al, 2009. The biological activity could be increased by the complexation with metal ions (Mohamed & Sharaby, 2007;Kremer et al, 2006).…”

“…For background and the biological activity of sulfonamide and its derivatives, see: Kremer et al (2006); Chumakov et al (2006); Mohamed & Sharaby (2007); Wang et al (2010); Sharaby (2007); Aziz-ur-Rehman et al (2010); Subashini et al (2009) ;Loughrey et al (2009). For a related structure, see : Fun et al (2010).…”