Synthesis and fungicidal activity of bis(2-arylcarbonylamino-1H-benzimidazol-5-yl) sulfones

4-[1-(Substituted aryl/alkyl carbonyl)-benzoimidazol-2-yl]-benzenesulfonic acids: Synthesis, antimicrobial activity, QSAR studies, and antiviral evaluation

“…The appearance of C]O stretch in the range of 1630e1600 cm À1 indicated the formation of tertiary amides (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20) by the reaction of acid chlorides with the 4-(1H-benzoimidazol-2yl)-benzenesulfonic acid. The primary amino group in compound 1 is depicted by the presence of NH asymmetric stretch at 3481.81 cm À1 .…”

“…Furthermore, the topological parameter, Balaban index (J) followed by the electronic parameter, LUMO and topological parameter, valence second order molecular connectivity index ( 2 c v ) is describing the antimicrobial activity of 4-[1-(substituted aryl/alkyl carbonyl)-benzoimidazol-2-yl]-benzenesulfonic acids (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20).…”

Synthesis of Sulfonated Dihydrofuropyrazoles Derivatives as Antimicrobial Active Agents

“…These are widely used as antimicrobial agents, antidiabetic agents, diuretics, anticonvulsants, antiretroviral and Hepatitis-C antiviral agents. Several researches revealed that the broad spectrum antimicrobial activity of sulfone containing heterocycles entities [2][3][4][5][6][7][8][9][10] Recently, Kudruavtsev et al [11] reported that the sulfone bearing pyrrolidine derivatives inhibits Staphylococcus aureus sortase SrtA isoform, irreversibly by modification of enzyme cys 184.…”