Synthesis and Hemocompatibilities of Cellulose-Containing Segmented Polyurethanes

Hanada, Tomohiro; Li, Yujun; Nakaya, Tadao

doi:10.1002/1521-3935(20010101)202:1<97::aid-macp97>3.0.co;2-c

Cited by 13 publications

(7 citation statements)

References 5 publications

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“…The characteristic absorption peaks of the PU are observed at 3300 cm À1 (N-H stretching frequency), 2927-2890 cm À1 (-CH 2 -stretching frequencies), 1734 cm À1 (carbonyl urethane stretching), 1540 cm À1 (CHN vibration), 1270 cm À1 (coupled C-N and C-O stretching), 825 cm À1 (aromatic C-H stretching) and 1079 cm À1 (C-O stretching). The characteristic peak for -NCO (2250-2275 cm À1 ) disappeared after polymerization, indicating polymerization reaction completion [19][20][21][22]. The absence of absorbance at 2267 cm À1 indicated that there were no unreacted isocyanate groups in the PU [18][19][20].…”

Section: Characterization Of Cla-based Pusmentioning

confidence: 99%

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Chlorogenic Acid Containing Bioinspired Polyurethanes: Biodegradable Medical Adhesive Materials

Ateş

Köytepe

Karaaslan

et al. 2015

International Journal of Polymeric Materials and Polymeric Biom

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Highly adhesive bioinspired polyurethanes (PUs) based on the chlorogenic acid (CLA) were prepared from 4,4 0 -methylenebis (cyclohexyl isocyanate) (MCI) and polyethylene glycol 200 (PEG 200). The polyurethanes exhibited the lowest glass transition temperature (T g ), improved thermal stability and good adhesive properties. The highest adhesion strength was found as 373.3 AE 47.5 kPa for 10% CLA containing PUs. The polyurethanes were observed to be biodegradable and were in the range of 19-24% for 8 weeks as depending on chlorogenic acid containing of PUs. As a result, prepared biocompatible-adhesive bioinspired polyurethanes are good candidates for medical applications as a tissue adhesive material.

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Section: Characterization Of Cla-based Pusmentioning

confidence: 99%

“…This phenomenon may be attributed to crosslinking of the quinic acid block came from CLA in the polymer structure. As a result, all the polyurethanes suitable for usage in medical application because of exhibit high thermal stability (Td > 280 C) [22][23][24][25][26].…”

Section: Characterization Of Cla-based Pusmentioning

confidence: 99%

Chlorogenic Acid Containing Bioinspired Polyurethanes: Biodegradable Medical Adhesive Materials

Ateş

Köytepe

Karaaslan

et al. 2015

International Journal of Polymeric Materials and Polymeric Biom

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“…The development of macromolecular syntheses from renewable carbon resources and the circulation system of the macromolecules are essential for human life 1. Thus acidic saccharide derivatives such as aldaric, aldonic, and alduronic acids have also been in use as starting blocks, for biomedical and/or biodegradable polymeric materials 2–24…”

Section: Introductionmentioning

confidence: 99%

Glycopolymeric inhibitors of β‐glucuronidase. III. Configurational effects of hydroxy groups in pendant glyco‐units in polymers upon inhibition of β‐glucuronidase

Hashimoto

Saito

Ohsawa

2006

J. Polym. Sci. A Polym. Chem.

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Two kinds of new glycopolymers, (P(VB‐1‐GlcaH‐co‐AAm), 9) and (P(VB‐1‐Glco‐co‐AAm), 10), were synthesized through the radical copolymerization of styrene derivatives bearing pendant D‐glucaric and D‐gluconic moieties, N‐(p‐vinylbenzyl)‐1‐D‐glucaramide (VB‐1‐GlcaH, 7), and N‐(p‐vinylbenzyl)‐D‐gluconamide (VB‐1‐Glco, 8), with acrylamide (AAm). Glycopolymer 9 bearing the pendant glucaric moiety at the first position inhibited the hydrolysis of a model compound for xenobiotics‐β‐glucuronide conjugates, p‐nitrophenyl β‐D‐glucuronide, uncompetitively, in contrast to the competitive inhibition in the presence of the corresponding isomeric glycopolymer bearing the pendant D‐glucaric unit at the sixth position (P(VB‐6‐GlcaH‐co‐AAm), 3) reported in our previous article. On the other hand, another copolymer 10 bearing the gluconic moiety was found not to inhibit the hydrolysis as well as the corresponding copolymer bearing pendant gulonic unit (P(VB‐6‐Glco‐co‐AAm), 4). These results indicate that the hydrolysis is influenced not only by existence of pendant carboxyl units but also by the direction on the linkage of the glyco‐units to the polymer frame. Therefore the configurational position of hydroxy groups in pendant glyco‐units in macromolecular inhibitors may be essential for the interaction with β‐glucuronidase. © 2006 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 44: 4895–4903, 2006

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“…The number of adhered platelet is sensitive also to the soft segment length in the case of fluorinated polyurethanes, (Wang & Wei, 2005). The presence of cellulose in segmented polyurethane matrix indeed inhibits platelet adhesion, (Hanada et al, 2001). For PU/hydrophilic poly(ethylene glycol)diacrylate IPNs, platelet adhesion is suppressed by microseparated IPN structure, (Yoon et al, 2005).…”

Section: Platelet Adhesionmentioning

confidence: 99%

Natural-Based Polyurethane Biomaterials for Medical Applications

Macocinschi¹,

Filip²,

Vlad³

2011

Biomaterials Applications for Nanomedicine

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Synthesis and Hemocompatibilities of Cellulose-Containing Segmented Polyurethanes

Cited by 13 publications

References 5 publications

Chlorogenic Acid Containing Bioinspired Polyurethanes: Biodegradable Medical Adhesive Materials

Chlorogenic Acid Containing Bioinspired Polyurethanes: Biodegradable Medical Adhesive Materials

Glycopolymeric inhibitors of β‐glucuronidase. III. Configurational effects of hydroxy groups in pendant glyco‐units in polymers upon inhibition of β‐glucuronidase

Natural-Based Polyurethane Biomaterials for Medical Applications

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