Synthesis and herbicidal activity of fluorinated N-phenylalkanesulfonamides

Abstract

or toxicological symptoms and all the birds remained healthy throughout the study. Feed consumption was significantly reduced at the 300 g/ton level and the birds in this group ended th$ medication period gaining 60% as much weight as the control group. There were no discernible differences in the quality of the eggs or the egg shell.

Determination of pKa values of fluoroalkanesulfonamides and investigation of their nucleophilicity

“…8.95 g of pure 1c (21.2 mmol, 92%) was obtained as a white solid by column chromatography on silica gel using dichloromethane as the eluent. 1 3284,1539,1361,1198,1180,1162,1131,1085,833,698,614,588,540,493, 428 cm À1 . Anal.…”

“…Since the discovery of Prontosil in 1932, a great deal of benzenesulfonylamides have been synthesized and found effective for the treatment of bacterial infections [1]. Common alkanesulfonylamides, however, found little application in the pharmaceutical or agrochemical area at that time [1].…”

“…Common alkanesulfonylamides, however, found little application in the pharmaceutical or agrochemical area at that time [1]. When fluorine was introduced into these common alkanesulfonylamides, their biological activity was satisfactorily improved [1][2][3][4].…”

“…Common alkanesulfonylamides, however, found little application in the pharmaceutical or agrochemical area at that time [1]. When fluorine was introduced into these common alkanesulfonylamides, their biological activity was satisfactorily improved [1][2][3][4]. For example, Trepka and Moore found that fluorinated N-phenylalkanesulfonylamides showed potent herbicidal and anti-inflammatory activities in 1970s [2][3][4].…”

CADASTER QSPR Models for Predictions of Melting and Boiling Points of Perfluorinated Chemicals

“…In addition, measurements obtained from other literature sources were also added. In case of MP , 19 data points from Trepka et al.,27 7 data points from Gajewski et al 28. and 13 from Platonov et al 29.…”