Synthesis and insecticidal activity of novel pyrimidine derivatives containing urea pharmacophore against Aedes aegypti

Abstract

A practical synthetic route for pyrimidine derivatives is presented. This study suggests that these pyrimidine derivatives exhibit some activity against the yellow fever mosquito and, with further structure modification, could be novel lead compounds for the development of insecticides against mosquitoes. © 2016 Society of Chemical Industry.

Synthesis and in vivo fungicidal activity of some new quinoline derivatives against rice blast

“…Previously, our group has synthesised a series of new compounds as pesticides . In this paper the fungicide tebufloquin was selected as a lead compound.…”

Design, synthesis and antifungal activity of threoninamide carbamate derivatives via pharmacophore model

“…In recent reference, her group 17 built a modelling of the P. capsici cellulose synthase 3. In our previous work [18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35] , many bioactive compounds were designed and synthesised. In this paper, based on the structure of seven commercialised CAA fungicides, we found that they have similar structural fragments: amide bond, para-substituted phenyl, 3,4-dialkyloxy substituted phenyl.…”

Synthesis and Fungicidal Activities of 2,3‐Dimethyl‐4‐(1‐acyloxy)alkoxy‐6‐tert‐butyl‐8‐fluoroquinolines

“…Heterocyclic compounds have become the mainstream of new pesticide research due to their wide range of biological activities, low toxicity, high efficiency, environmental friendliness, and structural diversity . Heterocyclic agrochemicals containing nitrogen has better activity, including insecticidal , antimicrobial , antiviral , fungicidal , and herbicidal . Quinolines are one of the most important compounds in nitrogen‐containing heterocycles and exhibited appreciable fungicidal activity .…”