Synthesis and properties of 1-aryl-2,5,7-trimethyl-4-oxo-1,4-dihydropyrido[2,3-d]pyrimidines

Substituted 2-aminonicotinamides in the synthesis of pyrido[2,3-d]pyrimidin-4(1H)-ones, 2,3-dihydropyrido- [2,3-d]pyrimidin-4(1H)-ones, and 11b,12-dihydropyrido- [2',3':4,5]pyrimido[2,1-a]isoindole-5,7-diones

“…Condensed pyridines are also used as plant protection agents [5], and in organic synthesis [6]. The synthesis of 2-substituted 1-phenylpyrido[2,3-d]pyrimidin-4(1H)-ones in low yield by the interaction of 2-(phenylamino)nicotinamides with acetic anhydride is described in the literature [7,8]. The present study is devoted to the development of methods of synthesis of new pyrido[2,3-d]pyrimidin-4(1H)-ones.…”