2015
DOI: 10.1039/c5py00181a
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Synthesis and properties of temperature-sensitive and chemically crosslinkable poly(ether-urethane) hydrogel

Abstract: The PEU-MA solutions can gelate at physiological temperature, and be further crosslinked by UV light.

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Cited by 8 publications
(4 citation statements)
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“…2,12 Hence, the modulation of PU-based hydrogels with PEG improves the biocompatibility, and enables the adjustment of degradability and mechanical properties by varying the molecular mass or concentration of the PEG. 7,13 The ability to design PU-based hydrogels using a biodegradable and biocompatible polymer building block, either natural 2,12,14 or synthetic, 2,12,15,16 is an essential feature in tailoring their biodegradability and biocompatibility. Natural polymers are generally biocompatible, however their poor mechanical properties, fast degradation rates, poor reproducibility and potential immunogenicity restrict their use.…”
Section: Introductionmentioning
confidence: 99%
“…2,12 Hence, the modulation of PU-based hydrogels with PEG improves the biocompatibility, and enables the adjustment of degradability and mechanical properties by varying the molecular mass or concentration of the PEG. 7,13 The ability to design PU-based hydrogels using a biodegradable and biocompatible polymer building block, either natural 2,12,14 or synthetic, 2,12,15,16 is an essential feature in tailoring their biodegradability and biocompatibility. Natural polymers are generally biocompatible, however their poor mechanical properties, fast degradation rates, poor reproducibility and potential immunogenicity restrict their use.…”
Section: Introductionmentioning
confidence: 99%
“…2,12 Hence, the modulation of PU-based hydrogels with PEG improves the biocompatibility, and enables the adjustment of degradability and mechanical properties by varying the molecular mass or concentration of the PEG. 7,13 The ability to design PU-based hydrogels using a biodegradable and biocompatible polymer building block, either natural 2,12,14 or synthetic, 2,12,15,16 is an essential feature in tailoring their biodegradability and biocompatibility. Natural polymers are generally biocompatible, however their poor mechanical properties, fast degradation rates, poor reproducibility and potential immunogenicity restrict their use.…”
Section: Introductionmentioning
confidence: 99%
“…Due to the biophysical similarity to living tissues and extracellular matrix, hydrogels have become particularly valuable for research studies on tissue engineering, 1,2 drug/gene delivery, 3,4 biocatalysis, 5 and regenerative medicine. 6,7 Among various different functional hydrogels, heparin-based hydrogels have shown promising prospects in diverse biomedical applications, such as antithrombogenic membranes and implants, 8,9 injectable hydrogels for cancer treatment therapy, 10 growth factor carriers promoting stem cell differentiation, 11,12 and heparin covalent or non-covalent bonded scaffolds for tissue regeneration.…”
Section: Introductionmentioning
confidence: 99%