Abstract:The development of methods for preparing novel adamantane derivatives is a current problem since representatives of this class of compound have a broad spectrum of physiological activity (psychostimulating, immunostimulating, anticancer, analgesic) and are used in medical practice as antiviral, anti-parkinsonian, and other preparations [1][2][3][4]. It is known that adamantyl-substituted pyrazole shows high antibacterial activity and is of interest as a chemotherapeutic agent [2].The 1,3-dipolar cycloaddition … Show more
N‐Nitroso CHF2‐pyrazolines were synthesized from in situ generated difluoromethyldiazomethane (CF2HCHN2), tert‐butyl isonitrite (tBuONO), and alkenes. The synthesis of representative CHF2‐pyrazoles and CHF2‐oxazolines was also performed.
N‐Nitroso CHF2‐pyrazolines were synthesized from in situ generated difluoromethyldiazomethane (CF2HCHN2), tert‐butyl isonitrite (tBuONO), and alkenes. The synthesis of representative CHF2‐pyrazoles and CHF2‐oxazolines was also performed.
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