Synthesis and Reactivity Studies of a New Reagent, Ethyltriphenylphosphonium Tribromide

An environmentally benign synthesis of Tetrabutylphosphonium tribromide (TBPTB) – a versatile and efficient phase transfer reagent for organic transformations

“…A while ago, the first phosphonium tribromide reagent, Ethyltriphenylphosphonium tribromide (ETPPTB) has been developed by our group and its reactivity has been studied (4). In continuation of our efforts to study this class of reagents, it has been realized that further work is required in terms of development of a range of such reagents and studies of its properties.…”

Synthesis, crystal structure, Hirshfeld surface analysis, DFT calculations and characterization of 1,3-propanediylbis(triphenylphosphonium) monotribromide as brominating agent of double bonds and phenolic rings

“…Therefore several tribromides have been synthesized. The most frequently used quaternary phosphonium tribromide reagents as efficient brominating agents are benzyltriphenyl phosphonium tribromide 22,23 , tridecylmethyl phosphonium tribromide 21 , ethyltriphenyl phosphonium tribromide 24 , 1,2-ethanediylbis(triphenylphosphonium) ditribromide 25 and methyltriphenylphosphonim tribromide 26 .…”

An Environment‐friendly Synthesis of 2,3‐Disubstituted‐2‐iminothiazoline‐4‐ones

“…The important intermediates in the synthetic route are isothiocyanates, which could be prepared from various substituted amines ( 1 ) and carbon disulfide ( 2 ), via an intermediate of dithiocarbamic acids salts or its ester using some other assisting reagents, such as Et 3 N, DABCO, FeSO 4 , methyl chloroformate, 1,2‐dipyridinium ditribromide‐ethane , ethyltriphenylphosphonium tribromide , tosyl chloride , di‐2‐pyridyl thionocarbonate , and 1,1′‐thiocarbonyldi‐2,2′‐pyridone , according to literatures . In this paper, isothiocyanates 4i and 4k have been prepared from fluoroanilines via triethylamine salts of dithiocarbamic acids ( 5i , 5k ) by methyl chloroformate (Scheme ) or a ditribromide reagent (Scheme ).…”