Synthesis, Antimicrobial and Antiinflammatory Activities of 4‐Oxothiazolidines and Their 5‐Arylidenes.

Abstract

Thiazole derivatives R 0260 Synthesis, Antimicrobial and Antiinflammatory Activities of 4-Oxothiazolidines and Their 5-Arylidenes. -Synthesized compounds (VII) and (VIII) show antimicrobial and antiinflammatory activity. Compounds (VIIa), (VIIb), (VIIIa) and (VIIIb) show the strongest activities. -(YADAV, R.; SRIVASTAVA, S. D.; SRIVASTAVA*, S. K.; Indian J.

Microwave Assisted Synthesis, Spectral Correlation and Antimicrobial Evaluation of Some Aryl Imines

“…Imine derivatives possess a wide range of biological activities 1,2,13,[15][16][17][18][19][20] . These multipronged activities are associated with different substituents and the unsaturation of C=N moiety in between the aryl rings.…”

“…Schiff's bases, derived from aromatic amines and aromatic aldehydes are reported to be involved in the study of asymmetric catalysis 3 , agnetic properties 4 , photochromism 5 , binding with DNA 6 , construction of supra molecular structures 7 , the study of activity against Ehrlichascites carcinoma (EAC) 8 the field of dyes and pigments 9 , the development of corrosion inhibitors 10 , anti-HIV 11 and in the evaluation of physical properties in the crystalline state 12 . Optically active imine derivatives possess multipronged biological activities such as antimicrobial 13 , anticancer 14 anti-tubularcular [15][16][17] , nematicidal-insecticidal 18 , anti-inflammatory and lipoxygenas 19 . The imine moieties are important intermediates and versatile starting materials for the synthesis of chiral amines 20 , pyrimidine derivatives 21 33,35 .…”

Synthesis, in Vitro Antimicrobial Activity of Schiff’s Base, Azetidinones and Thiazolidinones

“…Azetidinones are the very important class of compounds possessing a wide range of biological activities such as antibacterial [4], anti-inflammatory [5], antihyperlipidemic [6], anticancer [7], antimicrobial [8], antitumor [9], antitubercular [10] etc. Furthermore, thiazolidinone derivatives found to possess a wide spectrum of biological activities [11][12][13][14][15][16][17].…”

Perchloric acid catalyzed condensation of amine and aldehydes: Synthesis and antibacterial activities of some aryl (E)-imines

“…The imine starting materials and important intermediates were used for the synthesis of pharmacologically active heterocycles including triazoles, trizolones [20][21][22]. Optically active imine derivatives possess biological activities such as antimicrobial [23], anticancer [24], antiplasmodic-antihypoxic [25], antitubularcular [26], nematicidal insecticidal [17], anti-inflammatory and lipoxygenase [27]. Hence the authors have taken efforts to synthesis of some imines by perchloric acid catalyzed condensation of aryl amines with various substituted benzaldehydes.…”