Synthesis, antioxidant activities of the nickel(II), iron(III) and oxovanadium(IV) complexes with N2O2 chelating thiosemicarbazones

Oxovanadium(IV) complexes based onS-alkyl-thiosemicarbazidato ligands. Synthesis, characterization, electrochemical, and antioxidant studies

“…[6][7][8] Because minor structural diversities of oxovanadium(IV) complexes are significant for their biological role, a large number of complexes with various ligands having ONS, N 2 O, N 2 O 2 , S 2 O 2 donor sets were synthesized. [4,6,9] Thiosemicarbazones and also their metal-based complexes present a great variety of biological activity ranging from antitumor, [10,11] antiviral, [12] antibacterial [13], and antioxidant [14,15] activities. In recent years, N 2 O 2 chelating thiosemicarbazones have attracted much attention due to the cytotoxicity of their iron(III) complexes against K562 chronic myeloid leukemia cell line [16,17] and insulin-mimetic activity of an oxovanadium(IV) complex with these ligands.…”

“…[4,[22][23][24] However, there is a limited number of articles on oxovanadium(IV) complexes with N 2 O 2 chelating thiosemicarbazones having salicylaldehyde derivatives. [15,18,[25][26][27][28] Herein, we present four new N 2 O 2 -complexes of oxovanadium(IV) which were synthesized from 2-hydroxy-napthaldehyde-S-R-thiosemicarbazones (R: methyl, ethyl, propyl, or allyl) and salicyl aldehyde (Figure 1). The complexes were characterized by elemental analysis, magnetic measurements, electronic, FT-IR, 1 H-NMR, and electron paramagnetic resonance (EPR) spectra ( Figure 1).…”

cis-Dioxomolybdenum(VI) complexes of a new ONN chelating thiosemicarbazidato ligand; Synthesis, characterization, crystal, molecular structures and antioxidant activities

“…The TEAC values are 0.33 and 0.30 for 1 and 3, respectively. The differences arise from these methods functioning with different reactions [40][41][42][43].…”

Novel hybrids of 3-n-butylphthalide and edaravone: Design, synthesis and evaluations as potential anti-ischemic stroke agents

“…20,21 It was found that the Å OH scavenging activity of 10g (65.5100 U/mL) was significantly superior to that of Ticlid (15.0616 U/mL), ASP (30.6956 U/mL), NBP (16.2026 U/mL), Eda (25.2753 U/mL) and NBP together with Eda (36.8347 U/mL) at the same concentration of 10 lM. (Fig.…”