Synthesis, biocompatibility and mechanical properties of ZrO₂-Al₂O₃ ceramics composites

Abstract

This study evaluated cell viability, microhardness and flexural strength of two ceramic composites systems (ZA and AZ), pure alumina and zirconia. There were prepared homogeneous mixtures of 78wt%Al2O3+20wt%3Y-TZP+2wt%Al2O3w (AZ) and 80wt%3Y-TZP+18wt%Al2O3+2wt%Al2O3w (ZA), as well as 3Y-TZP (Z), pure Al2O3 (A) and commercial monolithic 3Y-TZP (Zc). Also mouse fibroblast cells 3T3-L1 and a MTT test was carried out at 24, 48 and 72 h. The surfaces were observed with SEM and the microhardness and three-point flexural strength values were estimated. The absolute microhardness values were: A>AZ>Z>Zc>ZA. Flexural strength of Zc, Z, and ZA were around double than AZ and A. All groups showed high biocompatibility trough cell viability values at 24, 48 and 72 h. Factors like grain shape, grain size and homogeneous or heterogeneous grain distributions may play an important role in physical, mechanical and biological properties of the ceramic composites.

Properties of zirconia-containing glass-ionomer cement

“…It was observed that the ionomer had larger and more irregular particles compared to the ZrO 2 particles. These results agreed with those reported in other studies [17,34,35]. Additionally, it was observed that the ZrO 2 particles appeared as agglomerates, without any significant difference between the different granulometries.…”

Structure and Surface Morphology Effect on the Cytotoxicity of [Al2O3/ZnO]n/316L SS Nanolaminates Growth by Atomic Layer Deposition (ALD)

“…Some authors have shown their cell viability for many potential applications [8,[14][15][16][17][18]. Similarly, Al 2 O 3 exhibits a biocompatible behavior and is a standard ceramic-ceramic articulation material, due to its hardness and its least wear compared to metals, it has been used as the femoral head for joint replacement through decades [13,19].…”

Интенсификация спекания и упрочнение керамических материалов ZrO 2 –Al 2 O 3 введением оксида Fe

“…Керамические материалы на основе системы иттрий стабилизированный диоксид циркония (Y-ZrO 2 )-оксид алюминия(Al 2 O 3 ) обладают уникальными свойствами: высокой прочностью при изгибе и трещиностойкостью (Y-ZrO 2 ) в сочетании с химической инертностью и твердостью (Al 2 O 3 ), что делает их широко востребованными в качестве конструкционной и функциональной керамики [1]. Такие материалы применяются в различных областях техники: в ответственных узлах в машиностроении, в авиакосмической отрасли, для медицинских инструментов и имплантатов [2][3][4]. К недостаткам технологии такой композиционной керамики относятся: высокая температура спекания (1600-1750°С), сопровождающаяся ростом зерна [5], необходимость длительных выдержек при высокой температуре [6] либо применение дорогостоящих электроимпульсного плазменного спекания [7] или горячего прессования [8].…”