Synthesis, characterization, and antibacterial activity of Cu NPs embedded electrospun composite nanofibers

Zhang, Chenglin; Li, Chunping; Bai, Jie; Wang, Junzhong; Li, Hongqiang

doi:10.1007/s00396-015-3640-6

Cited by 11 publications

(7 citation statements)

References 34 publications

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“…For some applications such as antibacterial filtration and wound dressing, antibacterial activity is a must. However, most polymer electrospun fiber mats do not possess intrinsic antibacterial properties, and antibacterial polymer electrospun fiber mats are usually prepared by incorporation of antibacterial agents, including antibiotics, biocides, metal and metal oxide nanoparticles, and chitosan …”

Section: Introductionmentioning

confidence: 99%

“…However, most polymer electrospun fiber mats do not possess intrinsic antibacterial properties, and antibacterial polymer electrospun fiber mats are usually prepared by incorporation of antibacterial agents, including antibiotics, biocides, metal and metal oxide nanoparticles, and chitosan. [6][7][8][9][10][11][12] Silver has long been used as an antibacterial agent owing to its broad-spectrum antibacterial activity, low toxicity to human cells, and environmentally friendly features. [13][14][15][16] It is widely used in medical and food-packaging materials.…”

Section: Introductionmentioning

confidence: 99%

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Antibacterial polycaprolactone electrospun fiber mats prepared by soluble eggshell membrane protein–assisted adsorption of silver nanoparticles

Liu

Liang

et al. 2016

J of Applied Polymer Sci

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Antibacterial polycaprolactone (PCL) electrospun fiber mats were prepared by coelectrospinning PCL with soluble eggshell membrane protein (SEP) in 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP), followed by adsorption of silver nanoparticles (Ag NPs) through hydrogen-bonding interaction between the amide groups of SEP and the carboxylic acid groups capped on the surfaces of Ag NPs. The PCL/SEP fiber mat was characterized by X-ray photoelectron spectroscopy, indicating the presence of some SEP on the fiber surface. The adsorption of Ag NPs was confirmed by transmission electron microscopy and quantitatively characterized by thermogravimetric analysis. The pH value of the silver sol used for adsorption is very important in view of the amount and dispersion state of Ag NPs adsorbed on the fibers. The Ag NP-decorated PCL/SEP fiber mats prepared at pH 3-5 exhibit strong antibacterial activity against both gram-negative Escherichia coli and gram-positive Bacillus subtilis. Antibacterial PCL fiber mats were also obtained similarly with the assistance of collagen (another protein) instead of SEP, showing that protein-assisted adsorption of Ag NPs is a versatile method to prepare antibacterial electrospun fiber mats.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Antibacterial polycaprolactone electrospun fiber mats prepared by soluble eggshell membrane protein–assisted adsorption of silver nanoparticles

Liu

Liang

et al. 2016

J of Applied Polymer Sci

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“…In this respect, CuNPs and AgNPs may add a clear benefit when embedded in electrospun PAN and cellulose fibers. Additionally, in this case, the blending approach is the most investigated; silver and copper salts [103][104][105], or preformed ZnO-CuO-NPs [106], are included in the electrospinning solution. An interesting alternative is represented by the cellulose nanofibers, because the high number of -OH groups offers a location for fibers functionalization, thus regulating the nanophases upload and their release.…”

Section: Inclusion Of Metal Nanophases As Biocidesmentioning

confidence: 99%

“…Table 1 reports a summary with some representative studies dealing with electrospun antimicrobial fibers embedding metal nanoparticles. [107] No matter the preparation method, all the above mentioned composite electrospun nanofibers have been proved to exert good antibacterial properties against many Gram-positive [70,92,97,99,[102][103][104][105][106][107][108]113,114] and Gram-negative [70,92,97,99,102,103,[105][106][107][108]113,114] species, as well as antifungal effect [70,[108][109][110]. The detailed analysis on the antibacterial mechanisms involved and the overview on the different antimicrobial tests is beyond the aim of this review; nevertheless, the readers interested in the topic can refer to [115][116][117][118][119][120].…”

Section: Inclusion Of Metal Nanophases As Biocidesmentioning

confidence: 99%

Electrospun Nanomaterials Implementing Antibacterial Inorganic Nanophases

et al. 2018

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Electrospinning is a versatile, simple, and low cost process for the controlled production of fibers. In recent years, its application to the development of multifunctional materials has encountered increasing success. In this paper, we briefly overview the general aspects of electrospinning and then we focus on the implementation of inorganic nanoantimicrobials, e.g., nanosized antimicrobial agents in electrospun fibers. The most relevant characteristics sought in nanoantimicrobials supported on (or dispersed into) polymeric materials are concisely discussed as well. The interesting literature issued in the last decade in the field of antimicrobial electrospun nanomaterials is critically described. A classification of the most relevant studies as a function of the different approaches chosen for incorporating nanoantimicrobials in the final material is also provided.

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“…Other nanoparticles with antimicrobial properties include copper [107], titanium dioxide (titania) and zinc oxide.…”

Section: Applications Of Nanoparticle-nanofiber Compositesmentioning

confidence: 99%

Electrospinning of Functional Nanofibers for Regenerative Medicine: From Bench to Commercial Scale

Mortimer¹,

Widdowson²,

Wright³

2018

Novel Aspects of Nanofibers

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Nanofibers are an important material for regenerative medicine as they have a commensurate morphology to that of the macromolecular matrix that supports and houses the growth of cells and tissues within the body. Electrospinning is widely used to fabricate non-woven structures on the nanoscale and the versatility of the technique has widened the application of nanofibers. This is due to ease of extending nanofiber functionality through the incorporation of active materials both during and after electrospinning. Recent developments in electrospinning devices, such as needle-free systems, have reinvigorated research as these advances now allow fabrication of nanofibers at commercial scales. The process of electrospinning has a number of operating parameters that are adjusted in optimisation to achieve ideal fibres and a multitude of instrument configurations can be adopted to achieve the required manufacture. The innate properties of nanofibers, such as high surface area to volume ratio, have many proven benefits for regenerative medicine and the chapter examines these before discussing how functionality can be further improved. Numerous materials can be incorporated in the manufacture of electrospun mats, however when choosing materials for regenerative medicine, biocompatibility and biodegradability are the dominant functionalities that are required.

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Synthesis, characterization, and antibacterial activity of Cu NPs embedded electrospun composite nanofibers

Cited by 11 publications

References 34 publications

Antibacterial polycaprolactone electrospun fiber mats prepared by soluble eggshell membrane protein–assisted adsorption of silver nanoparticles

Antibacterial polycaprolactone electrospun fiber mats prepared by soluble eggshell membrane protein–assisted adsorption of silver nanoparticles

Electrospun Nanomaterials Implementing Antibacterial Inorganic Nanophases

Electrospinning of Functional Nanofibers for Regenerative Medicine: From Bench to Commercial Scale

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