Synthesis, characterization, and application of [1-methylpyrrolidin-2-one-SO<sub>3</sub>H]Cl as an efficient catalyst for the preparation of α-aminophosphonate and docking simulation of ligand bond complexes of cyclin-dependent kinase 2

Mirzaei, Mehdi; Hasanpour, Maede; Sabbaghzadeh, Reihaneh

doi:10.1080/10426507.2016.1206101

Cited by 6 publications

(2 citation statements)

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“…Mirzaei and co‐workers [65] reported [1‐methylpyrrolidin‐2‐one‐SO 3 H]Cl ionic liquid for the synthesis of α‐Aminophosphonates containing benzothiazole moiety. (Scheme 15 )…”

Section: Catalyzed Processes As Green Approachmentioning

confidence: 99%

Recent Advances in the Synthesis of α‐Aminophosphonates: A Review

et al. 2021

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α-Aminophosphonates play an important role across several fields, including organic synthesis and various potential applications. This review paper surveys recent achievements in the synthesis of α-Aminophosphonates, it summarizes the main synthetic routes towards α-Aminophosphonates that are known and it describes their biological proprieties from January2010 till December 2020: Special attention is devoted to green chemical approaches including catalysts, ultrasonic and microwave irradiations. We hope this paper will be a useful resource for researchers and that it will help them to work in this emerging research area.

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“…Mirzaei and co‐workers [65] reported [1‐methylpyrrolidin‐2‐one‐SO 3 H]Cl ionic liquid for the synthesis of α‐Aminophosphonates containing benzothiazole moiety. (Scheme 15 )…”

Section: Catalyzed Processes As Green Approachmentioning

confidence: 99%

Recent Advances in the Synthesis of α‐Aminophosphonates: A Review

et al. 2021

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“…α-Aminophosphonates are considered to be the structural analogs of the corresponding esters of α-amino acids and have been reported to expend several pharmacological activities such as their potential usage as anticancer drugs, enzymes inhibitors, haptens of catalytic antibodies, pharmacologic agents, antifungals, insecticides, plant growth regulators, and anti-HIV agents [9].…”

Section: Reihaneh Sabbaghzadehmentioning

confidence: 99%

Physicochemical Properties of analogs α-Aminophosphonates Drugs Determined via Molecular Dynamics Simulation

Sabbaghzadeh

2019

Asian Pac J Cancer Biol

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Cyclin-dependent kinases (CDKs, play important roles in cell cycle regulation. Since deregulation of cyclins and/or alteration or absence of inhibitors has been associated with many cancers, there is strong interest in CDKs inhibitors that could play an necessary role in the discovery of a new family of antitumor agents. molecular modeling is used to design new materials, which the correct prediction of physical properties of realistic systems is required. Gromacs is an tool to perform molecular dynamics simulations and energy minimization of bimolecular systems which commonly consists of several tens to thousands of amino acid residues. From the simulations the first 100 ps were regarded as equilibration, leaving 900 ps for analysis purposes. Thermodynamic properties density, potential energy, temperature, and pressure are given. In this results tetramethyl((1,4-phenylenebis(azanediyl))bis((4-chlorophenyl)methylene))bis(phosphonate) was found to be the better selective known inhibitor for cyclin-dependent kinase2 because it shown lowest energy. The phosphoric acid moiety is considered to bind to the affected protein more actively than the corresponding carboxylic acid because of its di anionic character.

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LaCl₃⋅7H₂O as an Effective Catalyst for the Synthesis of α-Aminophosphonates under Solvent-Free Conditions and Docking Simulation of Ligand Bond Complexes of Cyclin-Dependent Kinase 2

Mirzaei

Sabbaghzadeh

2021

Polycyclic Aromatic Compounds

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Synthesis, characterization, and application of [1-methylpyrrolidin-2-one-SO₃H]Cl as an efficient catalyst for the preparation of α-aminophosphonate and docking simulation of ligand bond complexes of cyclin-dependent kinase 2

Cited by 6 publications

References 43 publications

Recent Advances in the Synthesis of α‐Aminophosphonates: A Review

Recent Advances in the Synthesis of α‐Aminophosphonates: A Review

Physicochemical Properties of analogs α-Aminophosphonates Drugs Determined via Molecular Dynamics Simulation

LaCl₃⋅7H₂O as an Effective Catalyst for the Synthesis of α-Aminophosphonates under Solvent-Free Conditions and Docking Simulation of Ligand Bond Complexes of Cyclin-Dependent Kinase 2

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Synthesis, characterization, and application of [1-methylpyrrolidin-2-one-SO3H]Cl as an efficient catalyst for the preparation of α-aminophosphonate and docking simulation of ligand bond complexes of cyclin-dependent kinase 2

Cited by 6 publications

References 43 publications

Recent Advances in the Synthesis of α‐Aminophosphonates: A Review

Recent Advances in the Synthesis of α‐Aminophosphonates: A Review

Physicochemical Properties of analogs α-Aminophosphonates Drugs Determined via Molecular Dynamics Simulation

LaCl3⋅7H2O as an Effective Catalyst for the Synthesis of α-Aminophosphonates under Solvent-Free Conditions and Docking Simulation of Ligand Bond Complexes of Cyclin-Dependent Kinase 2

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Synthesis, characterization, and application of [1-methylpyrrolidin-2-one-SO₃H]Cl as an efficient catalyst for the preparation of α-aminophosphonate and docking simulation of ligand bond complexes of cyclin-dependent kinase 2

LaCl₃⋅7H₂O as an Effective Catalyst for the Synthesis of α-Aminophosphonates under Solvent-Free Conditions and Docking Simulation of Ligand Bond Complexes of Cyclin-Dependent Kinase 2