Synthesis, characterization and thermal behaviour of solid-state compounds of folates with some bivalent transition metals ions

Dametto, P. R.; Ambrozini, Beatriz; Caires, Flávio Júnior; Franzini, Vanessa Pezza; Ionashiro, Massao

doi:10.1007/s10973-013-3276-z

Cited by 17 publications

(14 citation statements)

References 11 publications

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“…The molar conductance values of Cd (II)-HL, Zn (II)-HL and Cu (II)-HL chelates are found to be 143,125 and 115 Ω -1 mol -1 cm 2 respectively. These values refer to the 1:2 electrolytes and supported by the number of chloride ions detected in the proposed general formulae of these chelates [46][47][48][51][52][53][54].…”

Section: Molar Conductance Of Metal Chelatessupporting

confidence: 58%

“…This d-d transition band strongly favours a distorted octahedral geometry around the metal ion. This geometry is further supported by its magnetic susceptibility value (2.1 BM) 28-30 [46][47][48][51][52][53][54].…”

Section: Reflectance Spectra and Magnetic Susceptibilitymentioning

confidence: 60%

“…No experimental or theoretical investigations were found addressing NLO for the studied novel chelates; therefore, this triggered our interest to undertake this study. NLO properties is the key functions of frequency shifting, optical modulation, switching, laser, fiber, optical materials logic and optical memory for the emerging technologies in areas such as telecommunications, signal processing and optical inter connections [46][47][48][51][52][53][54]. In order to investigate the relationship between molecular structure and NLO, the polarizibilities and hyperpolarizibilities of the studied chelates are calculated using B3LYP/ GenECP level of theory (Table 8).…”

Section: Non-linear Optical Properties (Nlo)mentioning

confidence: 99%

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Synthesis, structural characterization, thermal behaviour and antimicrobial activity of copper, cadmium and zinc chelates of traizole-thiole ligand in comparison with theoretical molecular orbital calculations

Zayed

Nouman

2019

Egypt. J. Chem.

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T HIS research involved structural and molecular behaviour of the ligand HL, 4-amino-5-(2,2-dichloro-1-methylcyclopropyl)-4H-1,2,4-triazole-3-thiol toward the transition metal ions namely Cu (II), Cd(II) and Zn (II) had been studied using elemental analyses, magnetic, electronic, FT-IR, 1 H-NMR, XRD and Thermal analyses (TGA and DTA). The interpretation of practical data obtained had been evaluated and confirmed by theoretical molecular modelling. The computations had been done by software of Gaussian 09W package. The geometries of traizole-thiole ligand and its metal chelates were fully optimized using density functional theory B3LYP method. Their structures were confirmed via correlation between experimental and theoretical calculations. The ligand and its metal chelates biological activities had been tested against Gram-positive (Staphylococcus aureus ATTC 12600), Gram-negative (Escherichia coli ATTC 11775 and) bacteria, two fungus (Aspergillus flavus and Candida albicans).

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Section: Molar Conductance Of Metal Chelatessupporting

confidence: 58%

Section: Reflectance Spectra and Magnetic Susceptibilitymentioning

confidence: 60%

Section: Non-linear Optical Properties (Nlo)mentioning

confidence: 99%

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Synthesis, structural characterization, thermal behaviour and antimicrobial activity of copper, cadmium and zinc chelates of traizole-thiole ligand in comparison with theoretical molecular orbital calculations

Zayed

Nouman

2019

Egypt. J. Chem.

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“…2). In the first endothermic step, the hydration water is eliminated up to 130°C [51], while the coordination water molecules are eliminated up to 230°C [52]. The oxidative degradation of both ligands (acetate and triazolopyrimidine) occurs in the last step, that is not a single one but an overlapping of several processes, according to profile of both DTG and DTA curves.…”

Section: Thermal Behaviour Of Complexesmentioning

confidence: 99%

“…3). In the range 59-128°C hydration water molecules elimination occurs [51]. In the second step takes place the transformation of acetate into carbonate and degradation of 38 % from triazolopyrimidine ligand that corresponds with phenyl moiety elimination.…”

Section: Thermal Behaviour Of Complexesmentioning

confidence: 99%

Thermal behaviour of some biologically active species based on complexes with a triazolopyrimidine pharmacophore

Olar

Calu

Badea

et al. 2016

J Therm Anal Calorim

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A series of complexes of type M(pmtp)(CH 3 COO) 2 ÁnH 2 O ((1) M: Co, n = 4.5; (2) M: Ni, n = 3.5; (3) M: Cu, n = 0.5; (4) M: Zn, n = 0; pmtp: 5-phenyl-7-methyl-1,2,4-triazolo[1,5-a]pyrimidine) were synthesised by one-pot condensation. The complexes were characterized by elemental analysis, ESI-MS, IR, UV-Vis-NIR, EPR spectra, magnetic susceptibility at room temperature as well as thermogravimetric analysis. The modifications in the IR spectra of complexes are in accordance with the condensation process and indicate the triazolopyrimidine coordination as unidentate. The electronic and EPR spectra together with magnetic moments indicate an octahedral stereochemistry for paramagnetic ions, except for Cu(II) with a square pyramidal geometry. Processes such as water elimination, acetate into carbonate transformation, as well as oxidative degradation of the triazolopyrimidine derivative were evidenced during thermal decomposition. The complexes exhibited an improved antimicrobial activity in comparison with the ligand, on both planktonic and biofilm-embedded microbial cells. The best antimicrobial activity in both susceptible and resistant strains was obtained for complex (3) followed by complex (1), which can be related to both oxidation state and stereochemical versatility. At high concentrations, the Cu(II) complex exhibits both cytotoxicity on HT 29 tumour cell line and anti-inflammatory activity.

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Insight on thermal behaviour of new complexes of Ni(II), Cu(II) and Zn(II) with a bismacrocyclic ligand developed as biologically active species

Badea

Bucur

Chifiriuc

et al. 2016

J Therm Anal Calorim

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Synthesis, characterization and thermal behaviour of solid-state compounds of folates with some bivalent transition metals ions

Cited by 17 publications

References 11 publications

Synthesis, structural characterization, thermal behaviour and antimicrobial activity of copper, cadmium and zinc chelates of traizole-thiole ligand in comparison with theoretical molecular orbital calculations

Synthesis, structural characterization, thermal behaviour and antimicrobial activity of copper, cadmium and zinc chelates of traizole-thiole ligand in comparison with theoretical molecular orbital calculations

Thermal behaviour of some biologically active species based on complexes with a triazolopyrimidine pharmacophore

Insight on thermal behaviour of new complexes of Ni(II), Cu(II) and Zn(II) with a bismacrocyclic ligand developed as biologically active species

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