Synthesis, crystal structure and superoxide dismutase activity of [pyrrolidinium][Co(sulfathiazole)₃(pyrrolidine)]

Abstract

Synthesis, crystal structure and superoxide dismutase activity of [pyrrolidinium] [Co(sulfathiazole) 3 (pyrrolidine)], Journal of Coordination Chemistry, 62:6, 951-957,The preparation, spectroscopic properties and crystal structure of [pyrrolidinium] [Co(sulfathiazole) 3 (pyrrolidine)] are reported. The X-ray structure reveals tetrahedral geometry around cobalt. Three sulfathiazole ligands (each in a ,N-binding mode) occupy three positions, while the remaining position is occupied by a disordered pyrrolidine. A pyrrolidinium is also disordered. The superoxide dismutase mimetic activity of the complex was investigated using the indirect xanthine-xanthine oxidase-nitroblue tetrazolium method and compared to that of the native enzyme.

Copper(II) complexes of hydroxyflavone derivatives as potential bioactive molecule to combat antioxidants: synthesis, characterization and pharmacological activities

“…[30] The IR bands at 810-854 and 784-799 cm −1 , υ(H 2 O) of coordinated water, are an indication of the binding of the water molecule to the copper ion.…”

Synthesis, Characterization and Superoxide Dismutase Actwity of the Manganese(ii) Mixed Ligand Complexes Containing Sulfathiazole

“…Despite the crystalline nature of the products, neither proved suitable for Xray structure determination. However, an inspection of molecular models, along with consideration of the structure found previously by X-ray crystallography, for a similar complex [pyrrolidinium][Co(stz) 3 (pyrro)] 35 containing a N 4 donor set, suggested that [Mn(stz) 2 (pyrro) 2 ] and [Mn(stz) 2 (pipe) 2 ] may have tetrahedral geometry around central atom. The sulfathiazole ligand has several potential donor atoms, but due to steric constraints, it is probably acting as a monoanionic unidentate chelating agent.…”

In vitro and in vivo biochemical activities of novel copper complexes of chrysin derivatives of organosulfur compounds based potential therapeutic agent: design, synthesis, characterization and pharmacological studies

“…These bands can be attributed to n-* and -* transitions within the Schiff base molecule. The electronic spectrum of the corresponding [CuHL 4l (OAc)] complex in DMSO reveals a broad band at 558 nm assignable to 2 B 1g → 2 A 1g transition [50] which is characteristic of distorted square planar environment around the copper(II) ion (Fig. S2, Supplementary le).…”