Synthesis, in vitro Α-Glucosidase, and acetylcholinesterase inhibitory activities of novel Indol-Fused Pyrano[2,3-D]Pyrimidine compounds

Synthesis, molecular docking analysis and in vitro evaluation of new heterocyclic hybrids of 4-aza-podophyllotoxin as potent cytotoxic agents

“…Heterocycles, a class of cyclic organic compounds containing at least one ring hetero atom, have played an important role in pharmaceutical development due to their variety of biological activities such as anti-fungal, 1 antimicrobial, 2 anti-inflammatory, 3,4 anti-diabetic, 5 cytotoxic, 6,7 anti-tumor, anti-cancer, 8,9 anti-viral, 10 acetylcholinesterase inhibitory, 11 and SARS-CoV2 inhibitory activities. 12 To date, heterocycles have presented themselves as the basic core of most marketed drugs.…”