Synthesis of 4H-chromene, coumarin, 12H-chromeno[2,3-d]pyrimidine derivatives and some of their antimicrobial and cytotoxicity activities

Evaluation and Characterization of Fasciola hepatica Tegument Protein Extract for Serodiagnosis of Human Fascioliasis

“…Analysis of the isotypic responses of sera of fascioliasis patients to liver fluke tegumental extract revealed that the predominant antibodies elicited are IgG1 and IgG4, which are the antibody serotypes that also predominate against excretory-secretory products, crude whole-worm extract, and cathepsin-L1 (36,42,50,59). In contrast to other studies that found significantly higher levels of IgG4 than IgG1 in humans with chronic fascioliasis (42), in our study we found similar levels of both IgG antibodies, with mean IgG1 levels slightly higher than those of IgG4.…”

Crystal structure of 3-amino-8-methoxy-1-phenyl-1H-benzo[f]chromene-2-carbonitrile, C21H16N2O2

“…In recent years, they have attracted considerable attention due to their antimicrobial [2,3], antileishmanial [4][5][6][7][8][9], anticancer [10][11][12][13][14][15], antiproliferative [22], antioxidant [16][17][18], hypertensive [14], antitumor [19][20][21] effects and activities, as well as proving potentially useful in the treatment of Alzheimer's disease [23] and schizophrenia disorder [24].…”

Crystal structure of 3-amino-9-methoxy-1-phenyl-1H-benzo[f]chromene-2-carbonitrile, C21H16N2O2

“…Chromene and benzochromene derivatives have attracted considerable interest owing to their biological and pharmaceutical activities such as antibacterial [1][2][3], antifungal [4][5][6], vascular-disrupting [7], antioxidant [8,9], anticancer [10][11][12][13], estrogenic anticoagulant and antispasmolytic [14], antileishmanial [15], antiproliferative and apoptosis inducing [16][17][18][19].…”