Synthesis of 6-membered germacycles by intramolecular germylzincation of alkynes

Abstract

Intramolecular addition of Ge–H bonds across internal alkynes was performed in excellent yields (from 78 to 94% according to the structures) for the first time in one operation with high...

Intramolecular dearomative 1,4-addition of silyl and germyl radicals to a phenyl moiety

“…In some cases, however, such transformations were proven as powerful synthetic tools like the recent intramolecular addition of Ge radicals to an alkyne function reported by Durandetti and co-workers. 10 Dearomative 1,4-additions of radicals to benzene moieties resembling Birch-type reactivity are considered as promising tools for arene transformations. 9 c Reports from Harder, 11 Jones, 12 or Andrada 13 showcase this reaction mode for magnesium and aluminum compounds under reductive or photolytic conditions, clearly indicating the corresponding radicals to be the crucial intermediates (Scheme 2b).…”