Synthesis of d¹⁰ N-Heterocyclic Carbene Complexes with a Perimidine Scaffold

Abstract

N-Heterocyclic carbenes (NHCs) are vital auxiliary ligands for organometallic chemistry, and although many variants have been synthesized, by far the most common are based on fivemembered rings, such as imidazole or benzimidazole. Unlike NHC complexes built on five-membered rings, which are typically conjugated, exploration of six-membered-ring NHC variants has focused on nonconjugated versions, such as N,N′-diamidocarbenes. Reports of conjugated six-membered ring NHCs are limited to metal complexes with a perimidine scaffold that are in a narrow range of between six and eight d electrons (on metals from groups 8−10). This manuscript showcases the synthesis of four d 10 metal complexes with a perimidine scaffold. The gold and silver complexes have a linear geometry, while the copper and platinum complexes are three-coordinated. All complexes were characterized by single-crystal X-ray crystallography, multinuclear NMR, and additional spectroscopic methods.

Dibromo–Isonitrile and N-acyclic Carbene Complexes of Platinum(II): Synthesis and Reactivity

“…In addition to the neutral ligands, the leaving groups as well can play an important role in modulating the properties of anticancer complexes [11,12]. Considering the wide applications described for carbene metal complexes in both bioinorganics [13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30] and catalysis [31][32][33][34][35][36][37][38][39][40][41][42][43][44], we hereby describe the synthesis of new [PtBr 2 (PPh 3 )(CNR)] and [PtBr 2 (PPh 3 )(NAC)] compounds, in order to compare their properties with those of their chlorinated counterparts.…”