Synthesis of dysprosium/Mn–Cu ferrite binary nanocomposite: Analysis of structural, morphological, dielectric, and optomagnetic properties

Kanna, R. Rajesh; Sakthipandi, K.; Kumar, Ashok; Dhineshbabu, N. R.; Maraikkayar, S.M. Seeni Mohamed Aliar; Afroze, Aneesa; Jotania, Rajshree B.; Sivabharathy, M.

doi:10.1016/j.ceramint.2020.02.157

Cited by 43 publications

(3 citation statements)

References 48 publications

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“…By analyzing the characteristic absorption bands in FTIR spectra, the functional groups present in the nanoparticles and the ferrite phase can be identified, which helps in understanding their chemical structure and composition. The nature of the chemical bonds studied based on the vibrational frequency which depends on the cation mass, distance between cation and oxygen ion, and bonding force [ 45 ].…”

Section: Resultsmentioning

confidence: 99%

The role of thermal treatment and formulation on modifying the structural nature and optimizing certain physical features of coprecipitated superparamagnetic Co–Mn–Cr spinel ferrite

Elbashir,

Seada,

Meaz

et al. 2024

Heliyon

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Section: Resultsmentioning

confidence: 99%

The role of thermal treatment and formulation on modifying the structural nature and optimizing certain physical features of coprecipitated superparamagnetic Co–Mn–Cr spinel ferrite

Elbashir,

Seada,

Meaz

et al. 2024

Heliyon

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“…−140,41 In the spectra of Dy/Mn-P, the characteristic peaks at 1670, 1421, and 1290 cm -1 belonging to the stretching vibration of C=O, C-H, and C-N in traditional PVP framework, respectively. 42 Meanwhile, the absorption peak at 556 cm −1 in Dy/Mn-P was assigned to the stretching vibration of Mn-O and Dy-O, further demonstrating the successful preparation of Dy/Mn-P. 43,44 The pH-sensitive responsive of NPs under acidic conditions is beneficial in reducing the damage to normal tissues due to the tumor microenvironment which usually exhibits acidity. As shown in Figures 1E and S6, no significant particle size and PDI change were seen in Dy/Mn-P after incubating with acetate buffer solution with 10% FBS at pH = 7.5 for 72 h. Comparably, when Dy/Mn-P was exposed to acetate buffer solution (pH = 5.0), the size of Dy/Mn-P gradually increased and PDI also increased to 0.65, which indicated that Dy/Mn-P possess pH-sensitivity and easily disintegrated under acidic conditions.…”

Section: Synthesis and Characteristics Of Dy/mn-p Npsmentioning

confidence: 98%

A pH-Sensitive Nanoparticle as Reactive Oxygen Species Amplifier to Regulate Tumor Microenvironment and Potentiate Tumor Radiotherapy

Jiang,

et al. 2024

IJN

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Background: Radiotherapy is a widely used clinical tool for tumor treatment but can cause systemic toxicity if excessive radiation is administered. Although numerous nanoparticles have been developed as radiosensitizers to reduce the required dose of X-ray irradiation, they often have limitations, such as passive reliance on radiation-induced apoptosis in tumors, and little consider the unique tumor microenvironment that contributes radiotherapy resistance. Methods: In this study, we developed and characterized a novel self-assembled nanoparticle containing dysprosium ion and manganese ion (Dy/Mn-P). We systematically investigated the potential of Dy/Mn-P nanoparticles (NPs) as a reactive oxygen species (ROS) amplifier and radiosensitizer to enhance radiation therapy and modulate the tumor microenvironment at the cellular level. Additionally, we evaluated the effect of Dy/Mn-P on the stimulator of interferon genes (STING), an innate immune signaling pathway. Results: Physicochemical analysis demonstrated the prepared Dy/Mn-P NPs exhibited excellent dispersibility and stability, and degraded rapidly at lower pH values. Furthermore, Dy/Mn-P was internalized by cells and exhibited selective toxicity towards tumor cells compared to normal cells. Our findings also revealed that Dy/Mn-P NPs improved the tumor microenvironment and significantly increased ROS generation under ionizing radiation, resulting in a ~70% increase in ROS levels compared to radiation therapy alone. This enhanced ROS generation inhibited ~92% of cell clone formation and greatly contributed to cytoplasmic DNA exposure. Subsequently, the activation of the STING pathway was observed, leading to the secretion of pro-inflammatory immune factors and maturation of dendritic cells (DCs). Conclusion:Our study demonstrates that Dy/Mn-P NPs can potentiate tumor radiotherapy by improving the tumor microenvironment and increasing endogenous ROS levels within the tumor. Furthermore, Dy/Mn-P can amplify the activation of the STING pathway during radiotherapy, thereby triggering an anti-tumor immune response. This novel approach has the potential to expand the application of radiotherapy in tumor treatment.

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“…The obtained high intense peak at 35.5 o corresponds to plane values (201) respectively. The average crystallite size can be calculated from the Debye Scherrer equation [27][28].…”

Section: Xrd Analysismentioning

confidence: 99%

Structural, Optical and Electrical Properties of V2O5 Thin films at different Molarities by Spray pyrolysis method

Fathima

Punithavthy

et al. 2022

J. Nig. Soc. Phys. Sci.

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Nowadays, Semiconducting thin films are the efficient candidates for good optical and electrical properties. In this study, the thin films of pure V2O5 together with 2 different molarities were prepared through the method of spray Pyrolysis. The prepared thin films were characterized by spectrographic tools such as XRD, FT-IR, UV-Vis and Hall effect to study their, crystalline nature, Functional group, band gap, resistivity, conductivity and mobility of the flow of electrons respectively. The structural morphology of the synthesized thin films was discussed through the micrographic image obtained from Scanning electron microscopy together with their surface occupancy plots. The obtained minimum crystallite size is about 26.8 nm for 4% molarities. The morphological and structural studies show enhanced results for 4% sample which makes it a viable candidature for optical and electrical applications.

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Synthesis of dysprosium/Mn–Cu ferrite binary nanocomposite: Analysis of structural, morphological, dielectric, and optomagnetic properties

Cited by 43 publications

References 48 publications

The role of thermal treatment and formulation on modifying the structural nature and optimizing certain physical features of coprecipitated superparamagnetic Co–Mn–Cr spinel ferrite

The role of thermal treatment and formulation on modifying the structural nature and optimizing certain physical features of coprecipitated superparamagnetic Co–Mn–Cr spinel ferrite

A pH-Sensitive Nanoparticle as Reactive Oxygen Species Amplifier to Regulate Tumor Microenvironment and Potentiate Tumor Radiotherapy

Structural, Optical and Electrical Properties of V2O5 Thin films at different Molarities by Spray pyrolysis method

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