2016
DOI: 10.1039/c5ra24621k
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Synthesis of fluorescent nitrogen-doped carbon dots from dried shrimps for cell imaging and boldine drug delivery system

Abstract: Fluorescent N-doped carbon dots were synthesized using dried shrimps as precursors and rationally fabricated as a traceable drug delivery system for the targeted delivery of boldine to human breast cancer cells (MCF-7 cells).

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Cited by 123 publications
(36 citation statements)
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“…The size distribution of BCDs prepared from egg white was well controlled, and the quantum yield was greatly improved. Dried shrimp and pipe tobacco were also used as carbon sources to prepare N‐doped BCDs. Of course, in addition to the N‐doped, there is also S‐doped in heteroatom doping.…”
Section: Methods For the Synthesis Of Bcdsmentioning
confidence: 99%
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“…The size distribution of BCDs prepared from egg white was well controlled, and the quantum yield was greatly improved. Dried shrimp and pipe tobacco were also used as carbon sources to prepare N‐doped BCDs. Of course, in addition to the N‐doped, there is also S‐doped in heteroatom doping.…”
Section: Methods For the Synthesis Of Bcdsmentioning
confidence: 99%
“…A schematic representation of BCDs synthesis and its application in drug delivery are shown in Figure e. D'souza et al . used dried shrimp as the source material of BCDs and were reasonably made into a traceable drug delivery system for targeted delivery of crude in MCF‐7 cells.…”
Section: Applications Of Bcdsmentioning
confidence: 99%
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“…These functional groups are vary according to the raw materials which are used in the synthetic procedures [7].The CQDs have attracted much the attention from researchers due to: First of all, being of their eco-friendly, high biocompatible, chemically stable, low toxicity and highly soluble in water [8][9]. Secondly, the CQDs are characterized by the electronic and optical properties such as electron acceptor or donor, high photoluminescence, that have made it an important material in applications ,electronic, optical and sensing devices, bioimage, delivery of drug [10][11][12][13][14].Finally, the CQDs can be prepared using fast, low-cost method, and by from like natural raw materials or organic waste [15][16]. Indeed, this properties made CQDs are a good alternative to conventional semiconductors (CdS, CdSe, ZnS, etc.…”
Section: Introductionmentioning
confidence: 99%
“…This will make cancer treatments safer and more effective, and will reduce suffering in patients. [34][35][36] Herein, we hydrothermally synthesized blue photoluminescent N,P-CDs using adenosine triphosphate and graphene oxide as starting materials prepared from our improved Brodie method. 37,38 First, 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC$HCl) and N-hydroxysuccinimide (NHS) sufficiently activated the carboxyl surface of GO, and then ATP was graed onto GO by electrostatic interactions and chemical bonding.…”
Section: Introductionmentioning
confidence: 99%