Synthesis of Heterocyclic Thioamides and Copper(II) Coordination Compounds Based on Them

Abstract

Abstract.

Synthesis, Structure and Application of Mixed-Ligand Coordination Compounds of Copper(II) with Substituted Thioamides

“…To obtain coordination compounds of the general formula CuL 2 [6][7][8][9] and [Cu(HL 6-9 ) 2 X 2 ] 2 , the initial benzimidazole-2-N-arylcarbothioamides HL [6][7][8][9] were synthesized according to the procedure given in [1] and the initial dichlorotetraaminecopper(II) -via reaction between copper(II) chloride and concentrated solution of ammonium. Other used inorganic salts of copper(II) and organic solvents were of pure grade.…”

“…The content of copper(II) in the synthesized complexes I-X was determined by a complexometric titration with ethylenediaminetetraacetic acid (EDTA). The content of nitrogen was determined by an elemental analysis using Kjeldahl method, and sulfur content -using Sheniger method [4].…”

“…Previously, we have obtained and investigated the coordination compounds of copper(II) with benzimidazole-2-thiocarboxylic acid arylamides using the general scheme of the direct [1] and traditional [1,2] synthesis methods:…”

“…(1) 1 Vinnytsia National Technical University, 95, Khmelnytske shose, 21021 Vinnytsia, Ukraine 2 Vinnytsia National Pirogov Memorial Medical University 56, Pyrogova St., 21018 Vinnytsia, Ukraine * ranskiy@gmail.com Ó Ranskiy A., Gordienko O., Didenko N., Titov T., Khutko M., 2020 HL 1 : R 1 = H, R 2 = 4-OC 2 H 5 ; HL 2 : R 1 = H, R 2 = 2-Cl; HL 3 : R 1 = 2-CH 3 , R 2 = 4-CH 3 ; HL 4 : R 1 = H, R 2 = 3-CH 3 ; HL 5 : R 1 = H, R 2 = 3-CF 3 .…”

“…Depending on the copper(II) salt or powder copper, organic solvent and the reaction conditions (t, τ, pH) the coordination compounds of the general formula CuL 2 [2] and [ С u(HL)Cl 2 ] 2 •2CH 3 OH [1] were synthesized. The compounds were investigated by the XRD method and the dimer spatial structure was specified for [Сu(HL)Cl 2 ] 2 •2CH 3 OH.…”