Synthesis of highly stable luminescent molecular crystals based on (E)-2-((3-(ethoxycarbonyl)-5-methyl-4-phenylthiophen-2-yl)amino)-4-oxo-4-(p-tolyl)but-2-enoic acid

Abstract

The synthesis of (E)-2-((3-(ethoxycarbonyl)-5-methyl-4-phenylthiophen-2-yl)amino)-4-oxo-4-(p-tolyl)but-2-enoic acid was performed. This organic compound was used as a building block for the organic molecular crystals with highly stable photoluminescence at ambient conditions, which has been established during 10 years of exploitation.

Synthesis, intramolecular cyclization and anti-inflammatory activity of substituted 2-(2-(Furan-2-carbonyl)hydrazono)-4-oxobutanoic Acids

“…Furthermore, this method was applied to the synthesis of 3-(imino(thien-2-yl))furan-2(3H)ones derivatives, which include the pharmacophore fragment, Gewald aminothiophene [30] (Scheme 1). It was found that 2-(2-(4-R-benzoyl)hydrazono)-4-oxobutanoic and 2-(thiophen-2-ylamino)-4-oxobut-2-enoic acids and their derivativities exhibit analgesic [31,32], anti-inflammatory [16] antimicrobial activity [24] and photoluminescent properties [33,34]. We continue to search for new biologically active compounds with low toxicity [35] and expand the methods for the synthesis of 2,4-dioxobutanoic acid and 3-hydrazonofuran-2(3H)-one derivatives.…”

Synthesis and characterization of ZnBTC-based MOFs: effect of solvents and salt

“…Currently, various materials have been intensively studied in materials science, such as inorganic nanoparticles [1][2][3], molecular crystals [4][5][6], COF (covalent organic framework) [7,8]. Applications for these materials include electronics [9], cancer treatment [10], catalysis [11], etc.…”