Synthesis of Isomeric Bromothiazolylamines and the Use of Their Mercurated Derivatives as Fungicides and Bactericides

Synthesis, Reactivity and Antimicrobial Activity of a Series of 2-Arylamino-1,3-selenazoles

“…Purification was easily achieved by recrystallization from EtOH. Overall, this method is faster and less odorous than the isoselenocyanate route [26]. Given that no X-ray crystal structures of such arylselenoureas were so far reported, we determined the molecular structures of 2a-2c by X-ray diffraction (Figure 3a).…”

“…However, the position of the mercury atom in the products was not established with certainty. Both mercuration at position 5 of the heterocycle, as well as mercuration of the N-aryl rings were proposed [26,28,29]. We were therefore interested in the mercuration of selenazole derivatives, which to our knowledge have not been described at all and to numinously establish the position of mercuration.…”

Eco-friendly synthesis of 2-aminothiazoles using Nafion-H as a recyclable catalyst in PEG–water solvent system

“…The crude product, thus obtained was subjected to purification by column chromatography on silica gel (100-200 mesh size) using 25% ethyl acetate in petroleum ether as an eluent to yield 2-aminothiazoles, 3a-l. The structures of all products were unambiguously established on the basis of spectral analysis (IR, 1 H NMR, 13 C NMR, mass spectral data, elemental analysis) and melting point determination (19)(20)(21)(22)(23)(24).…”

Synthesis and Pharmacological Evaluation of Some Novel Imidazo[2,1‐b][1,3,4]thiadiazole Derivatives

“…[4,5-b]quinoxalinyl}-1,2,2-trimethylcyclopentane (5) is described in this paper. Since the introduction of bromine atom into thiazolo ring 21 augments considerably the antimicrobial properties of the system, bromination of 3 will be carried out to determine the effect of bromine on the biological activity of imidazo [2,1-b]thiadiazoles. trimethylcyclopentane (2) (obtained by cyclization of camphoryl-3-thiosemicarbazide (1) with conc.…”