Synthesis of molecularly imprinted polymers for extraction of fluoroquinolones in environmental, food and biological samples

Madikizela, Lawrence Mzukisi; Nomngongo, Philiswa N.; Pakade, Vusumzi Emmanuel

doi:10.1016/j.jpba.2021.114447

Cited by 29 publications

(8 citation statements)

References 146 publications

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“…99 Consequently, MIPs must be constructed with many compounds as templates to simultaneously remove most compounds in a group from water to overcome this restriction. 100 The eighth of the 12 principles of green analytical chemistry emphasizes the necessity for methods that enable the analysis of several chemical compounds, as opposed to techniques that only analyze one analyte at a time. 101 This further reduces the analysis costs.…”

Section: Molecularly Imprinted Polymers (Mips)mentioning

confidence: 99%

“…Pharmaceuticals do not exist in isolation in the environment; rather, they are mixed with various other compounds, some of which share physicochemical properties . Consequently, MIPs must be constructed with many compounds as templates to simultaneously remove most compounds in a group from water to overcome this restriction . The eighth of the 12 principles of green analytical chemistry emphasizes the necessity for methods that enable the analysis of several chemical compounds, as opposed to techniques that only analyze one analyte at a time .…”

Section: Molecularly Imprinted Polymers (Mips)mentioning

confidence: 99%

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Molecularly Imprinted Polymer-Based Adsorbents for the Selective Removal of Pharmaceuticals from Wastewater: Adsorption Kinetics, Isotherms, and Thermodynamics Studies

Nxumalo,

Mahlambi

2023

Ind. Eng. Chem. Res.

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The majority of pharmaceuticals are found in the environment as mixtures. However, a significant amount of these therapeutic compounds cannot be completely metabolized by the human body; thus, they are excreted through feces and urine and end up in wastewater treatment plants (WWTPs). The presence of pharmaceuticals and the degree to which they can be removed during wastewater treatment are now important research topics. Despite the adoption of various alternative technologies for the treatment of wastewater, the adsorption process is still regarded as a promising method due to its high efficiency, increased simplicity, and lower costs. Recent developments in the adsorption process involve the incorporation of an artificial molecularly imprinted polymer (MIP), which is a potent molecular receptor capable of selectively recognizing and removing pollutants. The MIP has advantageous characteristics, which include high affinity, predetermination, high stability, ease of preparation, and low cost. Notably, MIPs can be applied to the cleanup and preconcentration of analytes as the selective adsorbent of solid-phase extraction (SPE), magnetic solid phase extraction (MSPE), and dispersive solid-phase extraction (dSPE). Furthermore, MIPs can be produced as composite nanomaterials by employing nanoparticles (nanoMIP). The advancements of MIPs employed as sorbent materials for quantitative assessment and purification of pharmaceuticals in environmental water have been given most of the focus. Therefore, this study not only aims to present the fundamental ideas about the application of MIPs as sorbents but also gives an overview of the considerable initiatives made in recent years to enhance the performance of MIPs. Considering this, various current approaches to the development of MIP-based extraction techniques are detailed in the present review. This review also demonstrates how kinetics, thermodynamics, and isotherm models can be used to better understand the behavior of adsorbents and the adsorption process.

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Section: Molecularly Imprinted Polymers (Mips)mentioning

confidence: 99%

Section: Molecularly Imprinted Polymers (Mips)mentioning

confidence: 99%

Molecularly Imprinted Polymer-Based Adsorbents for the Selective Removal of Pharmaceuticals from Wastewater: Adsorption Kinetics, Isotherms, and Thermodynamics Studies

Nxumalo,

Mahlambi

2023

Ind. Eng. Chem. Res.

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“…Therefore, MIPs for SPE, also namely MISPE, have been widely applied for target compounds extraction of chem-biological samples, environmental pollutants, drug screening, food safety inspection, and so on. [206][207][208] Generally speaking, a typical MISPE procedure consists of four main steps: synthesis of suitable MIPs sorbent, package of SPE column and sample uploading, washing away interferents, and elution of target components. Considering the needs of desired shapes, binding sites, porosity, permeability, adsorption-specific surface area, and tolerance in organic solvent, diverse MITs have been adopted to fabricate tailor-made MIPs sorbents.…”

Section: Solid Phase Extraction (Spe)mentioning

confidence: 99%

“…Therefore, MIPs for SPE, also namely MISPE, have been widely applied for target compounds extraction of chem‐biological samples, environmental pollutants, drug screening, food safety inspection, and so on. [ 206 , 207 , 208 ]…”

Section: Biomedical Applicationsmentioning

confidence: 99%

Bio‐Inspired Imprinting Materials for Biomedical Applications

et al. 2022

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Inspired by the recognition mechanism of biological molecules, molecular imprinting techniques (MITs) are imparted with numerous merits like excellent stability, recognition specificity, adsorption properties, and easy synthesis processes, and thus broaden the avenues for convenient fabrication protocol of bio-inspired molecularly imprinted polymers (MIPs) with desirable functions to satisfy the extensive demands of biomedical applications. Herein, the recent research progress made with respect to bio-inspired imprinting materials is discussed in this review. First, the underlying mechanism and basic components of a typical molecular imprinting procedure are briefly explored. Then, emphasis is put on the introduction of diverse MITs and novel bio-inspired imprinting materials. Following these two sections, practical applications of MIPs in the field of biomedical science are focused on. Last but not least, perspectives on the remaining challenges and future development of bio-inspired imprinting materials are presented.

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“…As harmful substances continue to affect human health through biochemical reactions, the safety of ingredients in food and medicine has become a focus of increasing attention (Aydoğan et al, 2019;Madikizela et al, 2022). Especially with the improvement of people's living standards and the advancement of science and technology, growth-promoting hormones, antibiotics, pesticides, food additives, etc.…”

Section: Introductionmentioning

confidence: 99%

Functionalized monolithic columns: Recent advancements and their applications for high-efficiency separation and enrichment in food and medicine

Wang

Guo

et al. 2022

Front. Chem.

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The chromatographic column is the core of a high-performance liquid chromatography (HPLC) system, and must have excellent separation efficiency and selectivity. Therefore, functional modification materials for monolithic columns have been rapidly developed. This study is a systematic review of the recently reported functionalized monolithic columns. In particular, the study reviews the types of functional monomers under different modification conditions, as well as the separation and detection techniques combined with chromatography, and their development prospects. In addition, the applications of functionalized monolithic columns in food analysis, biomedicine, and the analysis of active ingredient of Chinese herbal medicines in recent years are also discussed. Also reviewed are the functionalized monolithic columns for qualitative and quantitative analysis. It provided a reference for further development and application of organic polymer monolithic columns.

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Synthesis of molecularly imprinted polymers for extraction of fluoroquinolones in environmental, food and biological samples

Cited by 29 publications

References 146 publications

Molecularly Imprinted Polymer-Based Adsorbents for the Selective Removal of Pharmaceuticals from Wastewater: Adsorption Kinetics, Isotherms, and Thermodynamics Studies

Molecularly Imprinted Polymer-Based Adsorbents for the Selective Removal of Pharmaceuticals from Wastewater: Adsorption Kinetics, Isotherms, and Thermodynamics Studies

Bio‐Inspired Imprinting Materials for Biomedical Applications

Functionalized monolithic columns: Recent advancements and their applications for high-efficiency separation and enrichment in food and medicine

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