2003
DOI: 10.1016/s0960-894x(02)01040-5
|View full text |Cite
|
Sign up to set email alerts
|

Synthesis of N,N′,N″-trisubstituted thiourea derivatives and their antagonist effect on the vanilloid receptor

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1

Citation Types

0
2
0

Year Published

2003
2003
2018
2018

Publication Types

Select...
5
2

Relationship

1
6

Authors

Journals

citations
Cited by 21 publications
(2 citation statements)
references
References 21 publications
0
2
0
Order By: Relevance
“…Because TRPV1 functions as an integral molecule detecting multiple modes of noxious stimuli, one can easily imagine that TRPV1 antagonists would have antinociceptive effects, especially in inflammatory pain [11,16,27,28]. Thus, many research groups are engaged in developing novel TRPV1 antagonists, although the therapeutically useful antagonists are not currently available [86][87][88][89][90][91][92][93][94][95][96].…”
Section: Development Of Sc0030 a Novel Non-vanilloid Trpv1 Antagonistmentioning
confidence: 99%
“…Because TRPV1 functions as an integral molecule detecting multiple modes of noxious stimuli, one can easily imagine that TRPV1 antagonists would have antinociceptive effects, especially in inflammatory pain [11,16,27,28]. Thus, many research groups are engaged in developing novel TRPV1 antagonists, although the therapeutically useful antagonists are not currently available [86][87][88][89][90][91][92][93][94][95][96].…”
Section: Development Of Sc0030 a Novel Non-vanilloid Trpv1 Antagonistmentioning
confidence: 99%
“…For example,benzyl]thiourea analogues ( Figure 1a) have been reported for their potent analgesic activity (Lee et al 2002(Lee et al , 2004. Another thiourea derivatives as N,N',N'-trisubstituted thiourea derivatives ( Figure 1b) have been reported as new efficient analgesic agents by antagonistic effects against vanilloid receptor (Park et al 2003). Shalas et al (2016) reported that 1-allyl-3-(2-chloro-benzoyl)thiourea ( Figure 1c) have a good analgesic activity.…”
Section: Introduc Onmentioning
confidence: 99%