Synthesis of New Piperazinyl and Piperidinolyl Substituted p-Chloranil Derivatives and their Reactions with Thiols

Ibis, Cemil; Ayla, Sibel Sahınler; Özkök, Funda; Bahar, Hrisi

doi:10.1080/10426507.2015.1071816

Cited by 4 publications

(3 citation statements)

References 15 publications

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“…MMC has a wide range of applications in the field of biology and material science. This substrate is considered as a frontier to synthesize varieties of bioactive compounds [ 38 , 39 ]. It is also indicated as a suitable matrix for the analysis of small molecular compounds [ 40 ].…”

Section: 7-mercapto-coumarinmentioning

confidence: 99%

Insight on Mercapto-Coumarins: Synthesis and Reactivity

El‐Sawy

Abdelwahab²,

Kirsch

2022

Molecules

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Mercapto (or sulfanyl)-coumarins are heterocycles of great interest in the development of valuable active structures in material and biological domains. They represent a highly exploitable class of compounds that open many possibilities for further chemical transformations. The present review aims to draw focus toward the synthetic applicability of various forms of mercapto-coumarins and their representations in pharmaceuticals and industries. This work covers the literature issued from 1970 to 2021.

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Section: 7-mercapto-coumarinmentioning

confidence: 99%

Insight on Mercapto-Coumarins: Synthesis and Reactivity

El‐Sawy

Abdelwahab²,

Kirsch

2022

Molecules

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“…Despite the relatively lower spotlight compared to its O -counterpart, 4-methylumbelliferone ( 4-MUB ), 7-MC proves to be chemically and bioactively promising in the field of biological and material sciences. Recognized as a frontier substrate, it serves as a versatile platform to synthesize a variety of bioactive compounds [ 22 , 23 ]. Moreover, its efficacy as a matrix for analyzing small molecular compounds is acknowledged [ 24 ].…”

Section: Introductionmentioning

confidence: 99%

Biocatalytic Synthesis of Coumarin S-Glycosides: Towards Non-Cytotoxic Probes for Biomedical Imaging and Sensing

Burrini,

Pâris,

Collet

et al. 2024

Molecules

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This study unveils an innovative method for synthesizing coumarin S-glycosides, employing original biocatalysts able to graft diverse carbohydrate structures onto 7-mercapto-4-methyl-coumarin in one-pot reactions. The fluorescence properties of the generated thio-derivatives were assessed, providing valuable insights into their potential applications in biological imaging or sensing. In addition, the synthesized compounds exhibited no cytotoxicity across various human cell lines. This research presents a promising avenue for the development of coumarin S-glycosides, paving the way for their application in diverse biomedical research areas.

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“…In this respect, many quinones were reacted with amines, thiols, alcohols, to produce amino-, azido, hydroxy-, thio-, halogeno-or alkyl-substituted quinones by using different solvents such as EtOH, MeOH, H2O, CH3CN, CH2Cl2, at room or reflux temperature (22)(23)(24)(25)(26). Recently, in our laboratory, some NH-/SR-substituted quinones were synthesized between the reaction of quinones and amines/thiols, and also the antifungal, antibacterial, antioxidant or anticancer activities of these compounds have been evaluated (27)(28)(29)(30).…”

Section: Introductionmentioning

confidence: 99%

Synthesis of Some Mono-, Bis- NH-substituted-1,4-Benzoquinones

Kaçmaz¹

2018

Journal of the Turkish Chemical Society Section A: Chemistry

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The preparation of new mono-and bis-NH-substituted-1,4-benzoquinones, namely 2,5bis (5,6-dimethylbenzo[d]thiazol-2-ylamino)cyclohexa-2,5-diene-1,4-dione (3), 2,5-bis(3-(2methylpiperidin-1-yl)propylamino)-3-chlorocyclohexa-2,5-diene-1,4-dione (6), 2-(4-tertbutylbenzylamino)-3,5,6-trichlorocyclohexa-2,5-diene-1,4-dione (9), 2-(4-fluorophenylamino)-6tert-butylcyclohexa-2,5-diene-1,4-dione (12) are reported. The synthesis of new quinone derivatives (3, 6, 9, 12) have been carried out from the reactions between quinones (pbenzoquinone (1), 2,6-dichloro-1,4-benzoquinone (4), tetrachloro-1,4-benzoquinone (7) or 2-tertbutyl-1,4-benzoquinone (10)) and different amines (2-amino-5,6-dimethylbenzothiazole (2), N-(3aminopropyl)-2-pipecoline (5), 4-tert-butylbenzylamine (8) or 4-fluoroaniline (11)). The new compounds were characterized by elemental analysis, mass spectrometry, IR, 1 H-NMR, 13 C-NMR spectroscopy.Cite this: Kaçmaz A. Synthesis of Some Mono-, Bis-NH-substituted-1,4-Benzoquinones. JOTCSA. 2018;5(2):963-70.

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Synthesis of New Piperazinyl and Piperidinolyl Substituted p-Chloranil Derivatives and their Reactions with Thiols

Cited by 4 publications

References 15 publications

Insight on Mercapto-Coumarins: Synthesis and Reactivity

Insight on Mercapto-Coumarins: Synthesis and Reactivity

Biocatalytic Synthesis of Coumarin S-Glycosides: Towards Non-Cytotoxic Probes for Biomedical Imaging and Sensing

Synthesis of Some Mono-, Bis- NH-substituted-1,4-Benzoquinones

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