Synthesis of New Substituted 5‐Methyl‐3,5‐diphenylimidazolidine‐2,4‐diones from Substituted 1‐(1‐Cyanoethyl‐1‐phenyl)‐3‐phenylureas.

Abstract

3-phenylureas. -(SEDLAK*, M.; KEDER, R.; HANUSEK, J.; RUZICKA, A.; J. Heterocycl. Chem. 42 (2005) 5, 899-906; Dep. Org. Chem., Fac. Chem. Technol., Univ. Pardubice, CZ-532 10 Pardubice, Czech Republic; Eng.) -A. Forchert 47-121

Recent Advances in the Synthesis of Hydantoins: The State of the Art of a Valuable Scaffold

“…142 The use of aminonitriles was described as well, the cyclization occurring in the presence of H 3 PO 4 , hydrolyzing at the same time the iminohydantoin intermediate. 143…”

A Facile Synthesis of N-Carbamoylamino Acids

“…Alternatively, this ureas can be obtained from amino acid esters and different isocyanates through condensation and hydrolysis. 11 Since the multistep synthetic procedures are not useful for synthesis of diverse combinatorial libraries the elaboration of one-pot procedures using O-silylated amino acids and triphosgene, 12 or solid-phase technique, 13 were developed. These methods utilize limited number of amino acids as starting materials.…”