2018
DOI: 10.1039/c8ra03649g
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Synthesis of non-toxic, biocompatible, and colloidal stable silver nanoparticle using egg-white protein as capping and reducing agents for sustainable antibacterial application

Abstract: For nearly a decade, silver nanoparticles (AgNPs) have been the most prevalent commercial nanomaterials products widely used in different biomedical applications due to their broad-spectrum antimicrobial activity.

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Cited by 45 publications
(21 citation statements)
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“…The oxidation of Ag NPs into Ag + ions assist their diffusion into the biological system or put oxidative stress to produce reactive oxygen species (ROS) that change the permeability of membranes, damage DNA/RNA, proteins and lipids and nally induce cytotoxicity in prokaryotic cells. 28,29 Therefore, investigation of the magnitude of ROS production in all three bacterial strains (Proteus vulgaris, Escherichia coli, and Klebsiella pneumoniae) in response to various concentrations (5, 10 & 20 mg) of Ag NPs, ciprooxacin and the plant extract is very important to quantify the level of toxicity in comparison to control experiments, and the results are presented in Fig. 5a-c.…”
Section: Resultsmentioning
confidence: 99%
“…The oxidation of Ag NPs into Ag + ions assist their diffusion into the biological system or put oxidative stress to produce reactive oxygen species (ROS) that change the permeability of membranes, damage DNA/RNA, proteins and lipids and nally induce cytotoxicity in prokaryotic cells. 28,29 Therefore, investigation of the magnitude of ROS production in all three bacterial strains (Proteus vulgaris, Escherichia coli, and Klebsiella pneumoniae) in response to various concentrations (5, 10 & 20 mg) of Ag NPs, ciprooxacin and the plant extract is very important to quantify the level of toxicity in comparison to control experiments, and the results are presented in Fig. 5a-c.…”
Section: Resultsmentioning
confidence: 99%
“…10,12,13,21 Table S1 † shows the comparative MIC values of Ag NPs available in the literature against various microbial strains. [35][36][37][38][39][40][41][42][43][44][45][46][47][48][49][50][51][52] As can be seen from the table, majority of the literature reported MIC values of Ag NPs against both bacteria and fungi in the mg mL À1 range. There are only a very few articles reporting the MIC values in the ng mL À1 range, which are closer to our current ndings.…”
Section: Resultsmentioning
confidence: 99%
“…[6] Egg-white proteins Ovalbumin, ovotransferrin, and ovomucoid can act as reducing and capping agents to produce AgNPs. [27] Plants Plant extracts can act as stabilizing or reducing agents and mediate reduction of metal salts to nanostructural elemental forms. They can contain biomolecules and organic compounds like alkaloids, flavonoids, saponins, steroids, and tannins, which can act as templating agents and be used successfully in the synthesis of several NPs.…”
Section: Secondary Metabolites From Organismsmentioning
confidence: 99%