Synthesis of Novel 3,5,7‐Triaryl‐5,6‐dihydro‐4H‐1,2,5‐triazepines.

Abstract

Synthesis of Novel 3,5,7-Triaryl-5,6-dihydro-4H-1,2,5-triazepines. -The addition of catalytic amounts TosOH enhances the yield of cyclocondensation products (IV). -(RAVINDRAN, G.; MUTHUSUBRAMANIAN*, S.; SELVARAJ, S.; PERUMAL, S.; J. Heterocycl. Chem. 44 (2007) 1, 133-136; Dep. Org. Chem., Madurai Kamaraj Univ., Madurai 625 021,Tamil Nadu, India; Eng.) -H. Haber 23-167

A convenient one pot synthesis of highly substituted piperidines through a Michael addition-aldol cyclization sequence

“…In continuation to our exploration on the synthetic utility of N,N-diphenacylaniline, [15][16][17][18] we investigated the reaction of this substrate with chalcones in the presence of a base. A mixture of 2-[(2-oxo-2-arylethyl)anilino]-1-aryl-1-ethanones 1 with different arylidene acetophenone 2 and a catalytic amount of sodium ethoxide was taken in a glass tube and mixed thoroughly.…”