Synthesis of novel amidoalkyl naphthol-based azo dyes and evaluation of their antimicrobial activities

Bananezhad, Behjat; Islami, Mohammad Reza; Khabazzadeh, Hojatollah

doi:10.1007/s13738-018-1563-0

Cited by 5 publications

(4 citation statements)

References 33 publications

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“…The 1-amidoalkyl-2-naphthols possess diverse biological properties, such as antiviral, antibacterial, antifungal, and antiparasitic qualities [18][19][20][21][22]. Furthermore, members of this family are promising antioxidants, which also show cholinesterase and α-glucosidase inhibitory activities [23][24][25].…”

Section: Amidoalkyl Naphthols As Bioactive Moleculesmentioning

confidence: 99%

“…In terms of antiviral properties, the most active compounds against avian influenza virus (H5N1) were found to be 3 and 5, which showed similar results to the control, zanamivir. Bananezhad and co-workers synthesized a series of 14 amidoalkyl naphthols bearing an azo-moiety and subjected them to in vitro antimicrobial assays [19]. It was observed that none of the derivatives showed better antibacterial activities than the reference drugs trimethoprim/sulfamethoxazole (SXT) and ciprofloxacin.…”

Section: Amidoalkyl Naphthols As Bioactive Moleculesmentioning

confidence: 99%

“…However, the results from the antifungal test were very promising, since five substances (compounds 6-10, Figure 3) exhibited better potencies against Aspergillus niger than the standard drugs fluconazole and miconazole. Bananezhad and co-workers synthesized a series of 14 amidoalkyl naphthols bearing an azo-moiety and subjected them to in vitro antimicrobial assays [19]. It was observed that none of the derivatives showed better antibacterial activities than the reference drugs trimethoprim/sulfamethoxazole (SXT) and ciprofloxacin.…”

Section: Amidoalkyl Naphthols As Bioactive Moleculesmentioning

confidence: 99%

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Amidoalkyl Naphthols as Important Bioactive Substances and Building Blocks: A Review on the Current Catalytic Mannich-Type Synthetic Approaches

Petkov

Simeonov

2023

Applied Sciences

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Currently, 1-amidoalkyl-2-naphthol derivatives are of increasing interest due to their biological activities and further use in the preparation of other important bioactive molecules, such as aminoalkyl naphthols and oxazines. The synthesis of 1-amidoalkyl-2-naphthol moiety is usually achieved by employing one-pot multicomponent Mannich reactions. This review covers the recent reports on 1-amidoalkyl-2-naphthols’ preparation with the use of different catalysts and summarizes the available published data for the period of the last 3 years. It also puts emphasis on the structure, synthetic transformation and biological importance of this class of products.

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Section: Amidoalkyl Naphthols As Bioactive Moleculesmentioning

confidence: 99%

Section: Amidoalkyl Naphthols As Bioactive Moleculesmentioning

confidence: 99%

Section: Amidoalkyl Naphthols As Bioactive Moleculesmentioning

confidence: 99%

See 1 more Smart Citation

Amidoalkyl Naphthols as Important Bioactive Substances and Building Blocks: A Review on the Current Catalytic Mannich-Type Synthetic Approaches

Petkov

Simeonov

2023

Applied Sciences

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“…The anticancer activities of these compounds have also been evaluated [35]. The derivation of these products has made interest because of their pharmaceutical activities [36,37] For example; 1-amido-alkyl-2-naphthols have been reported to show cardiovascular activity [38]. The hypertensive effect of these compounds is very familiar for researchers [39].…”

Section: Introductionmentioning

confidence: 99%

Synthesis of Bis (Benzoyl Acetone Ethylene Diimine) Schiff Base Complex of Nickel (II) Supported on Magnetite Silica Nano-Particles (Fe3O4@Sio2/Schiff-Base Of Ni (II)) and Using it as an Efficient Catalyst for Green Synthesis of 1-Amidoalkyl-2-Naphthol.

Setoodehkhah

Mazraati

Moradian

2021

Preprint

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In this research, magnetite nano-particles as the core are fabricated by co-precipitation method from Fe(II) and Fe(III) chloride salts and then the surfaces of the nano-particles are modified to improve their performance. These modifications include the coating of silica and then the second layer by 3-amino propyl triethoxy silane (APTES) which causes the functionalization of magnetite nanoparticles with –NH2 groups. In the next step, an aliphatic tetra-dentate N2O2 Schiff base was synthesized by condensation reaction between benzoyl acetone and ethylenediamine. Then this Schiff base is immobilized on the magnetite silica surfaces. This immobilized Schiff base was converted to the Ni (II) Schiff base complex by the reaction with Ni(II) acetate tetrahydrate. This Ni (II) Schiff base complex is immobilized on magnetite silica and shown as Fe3O4@SiO2/Schiff base of Ni (II). This cor-shell nano-structure is fully characterized by techniques such as FT-IR, VSM, XRD, FE-SEM, EDX, TGA-DTA, AAS, BET, and BJH. In the last step, this nano-catalyst is used as an efficient catalyst for the solvent-free synthesis of amido alkyl naphthols by the condensation reaction between an aldehyde, 2-naphthol, and an amide. The reaction was monitored by TLC. At the end of the reaction, the nano-catalyst was removed easily from the reaction mixture by an external magnet. The products of amido alkyl naphthols were identified by FT-IR and 1HNMR techniques. Finally, the percentage yield of the reaction is calculated by measuring the mass of 1-amidoalkyl-2-naphthol synthesized in the presence of the catalyst.

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Synthesis of Bis (Benzoyl Acetone Ethylene Diimine) Schiff Base Complex of Nickel (II) Supported on Magnetite Silica Nanoparticles (Fe3O4@SiO2/Schiff-Base of Ni(II)) and Using It as an Efficient Catalyst for Green Synthesis of 1-Amidoalkyl-2-Naphthols

Mazraati

Setoodehkhah

Moradian

2021

J Inorg Organomet Polym

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Synthesis of novel amidoalkyl naphthol-based azo dyes and evaluation of their antimicrobial activities

Cited by 5 publications

References 33 publications

Amidoalkyl Naphthols as Important Bioactive Substances and Building Blocks: A Review on the Current Catalytic Mannich-Type Synthetic Approaches

Amidoalkyl Naphthols as Important Bioactive Substances and Building Blocks: A Review on the Current Catalytic Mannich-Type Synthetic Approaches

Synthesis of Bis (Benzoyl Acetone Ethylene Diimine) Schiff Base Complex of Nickel (II) Supported on Magnetite Silica Nano-Particles (Fe3O4@Sio2/Schiff-Base Of Ni (II)) and Using it as an Efficient Catalyst for Green Synthesis of 1-Amidoalkyl-2-Naphthol.

Synthesis of Bis (Benzoyl Acetone Ethylene Diimine) Schiff Base Complex of Nickel (II) Supported on Magnetite Silica Nanoparticles (Fe3O4@SiO2/Schiff-Base of Ni(II)) and Using It as an Efficient Catalyst for Green Synthesis of 1-Amidoalkyl-2-Naphthols

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