Synthesis of Photoresponsive Dual NIR Two-Photon Absorptive [60]Fullerene Triads and Tetrads

Jeon, Sejin; Wang, Min; Tan, Loon‐Seng; Cooper, Thomas M.; Hamblin, Michael R.; Chiang, Long Y.

doi:10.3390/molecules18089603

Cited by 4 publications

(2 citation statements)

References 28 publications

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“…In contrast, a major disadvantage of fullerenes is their relatively poor absorption in the red or far-red regions of the visible spectrum, because their main absorption bands occur in the UV, blue, and green regions. But this drawback could be overcome in many ways, such as the attachment of light-harvesting antennae, which absorb in the red wavelengths [117] or the use of two-photon excitation [118, 119]. …”

Section: Photodynamic Inactivation and Nanotechnologymentioning

confidence: 99%

Advances in antimicrobial photodynamic inactivation at the nanoscale

2017

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The alarming worldwide increase in antibiotic resistance amongst microbial pathogens necessitates a search for new antimicrobial techniques, which will not be affected by, or indeed cause resistance themselves. Light-mediated photoinactivation is one such technique that takes advantage of the whole spectrum of light to destroy a broad spectrum of pathogens. Many of these photoinactivation techniques rely on the participation of a diverse range of nanoparticles and nanostructures that have dimensions very similar to the wavelength of light. Photodynamic inactivation relies on the photochemical production of singlet oxygen from photosensitizing dyes (type II pathway) that can benefit remarkably from formulation in nanoparticle-based drug delivery vehicles. Fullerenes are a closed-cage carbon allotrope nanoparticle with a high absorption coefficient and triplet yield. Their photochemistry is highly dependent on microenvironment, and can be type II in organic solvents and type I (hydroxyl radicals) in a biological milieu. Titanium dioxide nanoparticles act as a large band-gap semiconductor that can carry out photo-induced electron transfer under ultraviolet A light and can also produce reactive oxygen species that kill microbial cells. We discuss some recent studies in which quite remarkable potentiation of microbial killing (up to six logs) can be obtained by the addition of simple inorganic salts such as the non-toxic sodium/potassium iodide, bromide, nitrite, and even the toxic sodium azide. Interesting mechanistic insights were obtained to explain this increased killing.

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Section: Photodynamic Inactivation and Nanotechnologymentioning

confidence: 99%

Advances in antimicrobial photodynamic inactivation at the nanoscale

2017

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“…We have recently reported dual NIR nonlinear optical absorption activities of branched triad C 60 (>DPAF-C 18 )(>CPAF-C 2M ) and tetrad C 60 (>DPAF-C 18 )(>CPAF-C 2M ) 2 nanostructures, each consisting of hybrid light-harvesting antenna DPAF-C n and CPAF-C n moieties [14]. These two types of chromophores were designed to provide linear optical absorption [or one-photon absorption (1PA)] at 400 and 500 nm, respectively, which corresponds to 2PA excitation at 800 and 1000 nm, respectively.…”

Section: Introductionmentioning

confidence: 99%

Broadband Two-Photon Absorption Characteristics of Highly Photostable Fluorenyl-Dicyanoethylenylated [60]Fullerene Dyads

Jeon

Wang

et al. 2016

Molecules

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Abstract:We synthesized four C 60 -(light-harvesting antenna) dyads C 60 (>CPAF-C n ) (n = 4, 9, 12, or 18) 1-C n for the investigation of their broadband nonlinear absorption effect. Since we have previously demonstrated their high function as two-photon absorption (2PA) materials at 1000 nm, a different 2PA wavelength of 780 nm was applied in the study. The combined data taken at two different wavelength ranges substantiated the broadband characteristics of 1-C n . We proposed that the observed broadband absorptions may be attributed by a partial π-conjugation between the C 60 > cage and CPAF-C n moieties, via endinitrile tautomeric resonance, giving a resonance state with enhanced molecular conjugation. This transient state could increase its 2PA and excited-state absorption at 800 nm. In addition, a trend of concentration-dependent 2PA cross-section (σ 2 ) and excited-state absorption magnitude was detected showing a higher σ value at a lower concentration that was correlated to increasing molecular separation with less aggregation for dyads C 60 (>CPAF-C 18 ) and C 60 (>CPAF-C 9 ), as better 2PA and excited-state absorbers.

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The photocytotoxicity effect of cationic sulfonated corrole towards lung cancer cells: in vitro and in vivo study

Zhao

Huang

et al. 2019

Lasers Med Sci

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Synthesis of Photoresponsive Dual NIR Two-Photon Absorptive [60]Fullerene Triads and Tetrads

Cited by 4 publications

References 28 publications

Advances in antimicrobial photodynamic inactivation at the nanoscale

Advances in antimicrobial photodynamic inactivation at the nanoscale

Broadband Two-Photon Absorption Characteristics of Highly Photostable Fluorenyl-Dicyanoethylenylated [60]Fullerene Dyads

The photocytotoxicity effect of cationic sulfonated corrole towards lung cancer cells: in vitro and in vivo study

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