Synthesis of silver nanoparticles and the antibacterial and anticancer activities of the crude extract of sargassum polycystum C. Agardh

Nallamuthu, Thangaraju; Venkatalakshmi, R; Chinnasamy, Arulvasu; Pandian, K.

doi:10.5101/nbe.v4i2.p89-94

Cited by 9 publications

(2 citation statements)

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“…AgNPs also play an efficient role during in vitro and in vivo treatments of lung cancer, cervical cancer, hepatocellular carcinoma, breast cancer, nasopharyngeal carcinoma, prostate carcinoma, colorectal adenocarcinoma, and glioblastoma 4 , 12 . Recently, AgNPs have been used in anticancer therapies of the Hep-2 cell line, HT-29 cell lines 13 , Vero cell line 14 , and breast cancer line MCF-7 15 .…”

Section: Introductionmentioning

confidence: 99%

Anticancer and antimicrobial activity of biosynthesized Red Sea marine algal silver nanoparticles

Algotiml

Gab-Alla

Seoudi

et al. 2022

Sci Rep

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Biosynthesis of silver nanoparticles (AgNPs) is emerging as a simple and eco-friendly alternative to conventional chemical synthesis methods. The role of AgNPs is expanding as antimicrobial and anticancer agents, sensors, nanoelectronic devices, and imaging contrast agents. In this study, biogenic AgNPs were synthesized using extracts of different marine algae species, including Ulva rigida (green alga), Cystoseira myrica (brown alga), and Gracilaria foliifera (red alga), as reducing and capping agents. The Physiochemical properties, cytotoxicity, anticancer and antimicrobial activities of the biosynthesized AgNPs were assessed. Surface plasmonic bands of the biosynthesized AgNPs capped with U. rigida, C. myrica, and G. foliifera extracts were visually observed to determine a colour change, and their peaks were observed at 424 nm, 409 nm, and 415 nm, respectively, by UV–Vis spectroscopy; transmission electron microscopy (TEM) indicated an almost spherical shape of AgNPs with nanoscale sizes of 12 nm, 17 nm, and 24 nm, respectively. Fourier transform-infrared (FTIR) spectroscopy analysis suggested that different molecules attached to AgNPs through OH, C=O, and amide groups. The major constituents of the aqueous algal extracts included, terpenoids, polyphenols, sulfonates, polysaccharides, fatty acids, chlorophylls, amide proteins, flavonoids, carotenoids, aliphatic fluoro compounds, volatile compounds, alkalines, pyruvic acid and agar groups. The cytotoxicity and anticancer activities of the biosynthesized AgNPs were assessed using Artemia salina nauplii, normal skin cell lines (HFb-4), and breast cancer cell lines (MCF-7 cell line). The lethality was found to be directly proportional to the AgNP concentration. The IC50 values of C. myrica and G. foliifera AgNPs against A. saline nauplii were 5 and 10 μg ml−1 after 4 h and 16 h, respectively, whereas U. rigida AgNPs did not exhibit cytotoxic effects. Anticancer activity of the biosynthesized AgNPs was dose dependent. The IC50 values of the biosynthesized AgNPs were 13, 13, and 43 µg ml−1 for U. rigida, C. myrica, and G. foliifera, respectively. U. rigida AgNPs particularly exhibited potent anticancer activity (92.62%) against a human breast adenocarcinoma cell line (MCF-7) with high selectivity compared the normal cells (IC50 = 13 µg/ml, SI = 3.2), followed by C. myrica AgNPs (IC50 = 13 µg/ml, SI = 3.07). Furthermore, the biosynthesized AgNPs exhibited strong antifungal activity against dermatophyte pathogenic moulds and mild antibacterial activity against the food borne pathogen bacteria. The highest antimicrobial activity was recorded for the U. rigida AgNPs, followed by those capped with C. myrica and G. foliifera extracts, respectively. AgNPs capped with the U. rigida extract exhibited the highest antimicrobial activity against Trichophyton mantigrophytes (40 mm), followed by Trichosporon cataneum (30 mm) and E. coli (19 mm), with minimal lethal concentration of 32 and 64 μg ml−1 respectively. The study finally revealed that extracts of marine algal species, particularly U. rigida extracts, could be effectively used as reducing agents for the green synthesis of AgNPs. These AgNPs are considered efficient alternative antidermatophytes for skin infections and anticancer agents against the MCF-7 cell line.

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Section: Introductionmentioning

confidence: 99%

Anticancer and antimicrobial activity of biosynthesized Red Sea marine algal silver nanoparticles

Algotiml

Gab-Alla

Seoudi

et al. 2022

Sci Rep

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“…(Thangaraju, Venkatalakshmi et al, 2012). Within 48 hours, the color of the metal ion solution in the flask containing bacterial culture filtrate changed.…”

Section: Synthesis Of Iron Oxide Npsmentioning

confidence: 99%

Bacteria-Mediated Synthesis of Iron Oxide Nanoparticles and Their Efficiency in Ammonia Removal from Fish Culture Tanks

Barik,

Saharan,

Krishnani

et al. 2023

IJAR

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Background: Aquaculture is one of the most rapidly expanding food production sectors. Due to intensification, declining water quality parameters negatively impact fish production and the surrounding environment. Thus, it is essential to maintain optimum water quality parameters and aquatic ecosystems for sustainable fish production. This study aims to synthesize nanoparticles (NPs) and evaluate their efficiency against ammonia in cultured fish tanks under diverse conditions. Methods: Bacillus megaterium from the soil sample was isolated and identified. Iron oxide NPs were synthesized using Bacillus megaterium collected from soil samples and characterized by DLS-zeta potential, UV-vis, XRD, FTIR, and TEM analysis. Next, synthesized NPs were evaluated under ex-situ and in-situ conditions to determine their efficacy in removing ammonia from Common carp, Cyprinus carpio culture tanks. Results: B. megaterium was isolated, identified, and 16S rRNA gene PCR-amplified sequences confirm the identification of B megaterium. DLS-zeta potential, UV-vis, XRD, FTIR, and TEM analysis revealed the quality of synthesized NPs. B. megaterium from the soil sample was isolated and identified. The mean zeta potential of the biosynthesized NPs was between -4.65 to -6.45 mV and had an average size of 5 nm. The concentration of ammonia in aerated tanks treated with iron NPs reduced to less than 0.03 mg/dL from 0.3 mg/L. Also, fish mortality in these tanks was significantly controlled with the application of NPs. The application of NPs considerably reduced fish mortality in these fish tanks. Iron oxide NPs from B. megaterium can produce high-quality NPs that are efficient in removing ammonia from fish culture tanks. Further, exploratory studies are necessary to determine the efficacy of iron oxide NPs on aquatic organisms cultured in different environments.

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Algal Nanoparticles: Synthesis and Characterization

Shera

Banik

2021

Nanotechnology in the Life Sciences

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Synthesis of silver nanoparticles and the antibacterial and anticancer activities of the crude extract of sargassum polycystum C. Agardh

Cited by 9 publications

References 0 publications

Anticancer and antimicrobial activity of biosynthesized Red Sea marine algal silver nanoparticles

Anticancer and antimicrobial activity of biosynthesized Red Sea marine algal silver nanoparticles

Bacteria-Mediated Synthesis of Iron Oxide Nanoparticles and Their Efficiency in Ammonia Removal from Fish Culture Tanks

Algal Nanoparticles: Synthesis and Characterization

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