Synthesis of silver nanowires in a two‐phase system for biological applications

Abstract

The ability to design nanowires (NW) in powder technology provides a great advantage for many applications in a variety of fields ranging from medicine to materials science. In this study, nanoparticles were synthesized simultaneously by using an aqueous two‐phase system, which was an environmentally friendly method since the reducing agent that was not spent in the reaction could be effectively recycled and reused. AgNWs (silver nanowires) with numerous high widths and dyes were easily synthesized between two phases using the 5,8‐dibromo‐2‐(butylamino)naphthalene‐1,4‐dione, a 2‐substituted naphthoquinone. Naphthoquinones are known as reducing agents in the production of metal nanoparticles. Synthesized NWs have an average diameter of 90 nm and an average length of 6 μm. The nanowires produced had a round cross section. Characterization of nanowires and nanoparticles was done with UV‐vis, XRD pattern, SEM, and EDX. As a result of characterization, it showed two relatively sharp absorbances in the UV‐vis spectrum at a wavelength of ~358 and 432 nm. In the XRD analysis, five basic peaks attributed to Ag nanoparticles were observed. When SEM images were analyzed, it was determined that Ag nanowires generally have an average diameter of 90 nm and an average length of 6 μm. Anticancer activity test was performed using the MTT test in the HeLa and HT‐29 cell lines. IC50 value was calculated as 11.54 and 16.07 μg ml, and AgNWs showed anticancer properties at high concentration. Evaluating the influence of AgNWs for the first time, this study has indicated that AgNWs exhibit inhibitory properties on the collagenase enzyme. It was observed that the IC50 rate for the enzyme activity was 346.5 mM (r2: 0.955), and Ki value was 41.09 mM.

Cytotoxicity and genotoxicity of green synthesized silver, gold, and silver/gold bimetallic NPs on BHK‐21 cells and human blood lymphocytes using MTT and comet assay

“…Different properties such as electrical, physical, optical, and chemical significantly affect the size and shapes of NPs. Nowadays, NPs mostly silver (Ag) and gold (Au) NPs are extensively used in biomedical, [ 14 ] drug delivery, [ 15 ] agriculture, [ 16 ] antioxidant, [ 17 ] anticancer, antibacterial, and antifungal, antibiofilm. [ 18,19 ] Nowadays, plant‐based synthesis of Ag, Au NPs, and Ag/Au BNPs is emergent because of its simplicity, cost‐effectiveness, and environmentally compassionate synthesis protocols.…”

Statistically Optimized Production of Saccharides Stabilized Silver Nanoparticles Using Liquid–Plasma Reduction Approach for Antibacterial Treatment of Water

“…Various methodologies have been reported in the literature to synthesize metal nanoparticles, including hydrothermal method [ 6 ], sol-gel method [ 7 ], photodetection technique [ 8 ], ultraviolet irradiation method [ 9 ], electrochemical technique [ 10 ], porous materials template [ 11 ], solvothermal method [ 12 ], chemical synthesis [ 13 ], microwave plasma treatment [ 14 ], polyol process [ 15 ], green synthesis [ 16 , 17 ] coaxial electro-spinning [ 18 ] and liquid plasma interaction technique [ 19 ]. Each approach has its own set of advantages and disadvantages, including differences in process cost, quantity, functionality and particle size distribution.…”

Optimization of a silver-nanoprism conjugated with 3,3′,5,5′-tetramethylbenzidine towards easy-to-make colorimetric analysis of acetaldehyde: a new platform towards rapid analysis of carcinogenic agents and environmental technology

“…Anisotropic noble metal nanoparticles have the extraordinary structural, surface, and photonic properties that have attracted much attention in optical chemosensors today. 35–50 Nanomaterials, such as metal nanoparticles, are identified by their different physical and chemical properties. 51 These characteristics are directly proportional to the surface/volume ratio.…”