Synthesis of sulfonimide-based dendrimers and dendrons possessing mixed 1 → 2 and 1 → 4 branching motifs

Kolotylo, Mykola V.; Holovatiuk, V. M.; Bondareva, Julia; Lukin, Oleg; Rozhkov, Vladimir V.

doi:10.1016/j.tetlet.2018.12.052

Cited by 5 publications

(2 citation statements)

References 12 publications

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“…Dendrimers and dendritic nanostructures attract much attention in biochemistry, nanotechnology, and pharmaceutical sciences, due to the possibility to precise control of its size, shape, and location of functional groups [34,35]. Dendrimers play an important role in biomedicine, as contrast agents, gene-transfection agents, and antibacterial substrates [36].…”

Section: Dendrimers and Dendritic Nanostructuresmentioning

confidence: 99%

Nanomaterials Interaction with Cell Membranes: Computer Simulation Studies

Цуканов

Vasiljeva

2020

Springer Tracts in Mechanical Engineering

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This chapter provides a brief review of computer simulation studies on the interaction of nanomaterialswith biomembranes. The interest in this area is governed by the variety of possible biomedical applications of nanoparticles and nanomaterials as well as by the importance of understanding their possible cytotoxicity. Molecular dynamics is a flexible and versatile computer simulation tool, which allows us to research the molecular level mechanisms of nanomaterials interaction with cell or bacterial membrane, predicting in silico their behavior and estimating physicochemical properties. In particular, based on the molecular dynamics simulations, a bio-action mechanism of two-dimensional aluminum hydroxide nanostructures, termed aloohene, was discovered by the research team led by Professor S. G. Psakhie, accounting for its anticancer and antimicrobial properties. Here we review three groups of nanomaterials (NMs) based on their structure: nanoparticles (globular, non-elongated), (quasi)one-dimensional NMs (nanotube, nanofiber, nanorod) and two-dimensional NMs (nanosheet, nanolayer, nanocoated substrate). Analysis of the available in silico studies, thus can enable us a better understanding of how the geometry and surface properties of NMs govern the mechanisms of their interaction with cell or bacterial membranes.

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Section: Dendrimers and Dendritic Nanostructuresmentioning

confidence: 99%

Nanomaterials Interaction with Cell Membranes: Computer Simulation Studies

Цуканов

Vasiljeva

2020

Springer Tracts in Mechanical Engineering

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“…Interestingly, all synthetic routes involving isocyanate and non‐isocyanate approaches to construct aliphatic polyurethane dendrimers strictly apply 1→2‐C branching motifs (Figure ). To the best of our knowledge, no reports are known on use of 1→4‐C branching motifs, although polyphenylene and sulfonimide based dendrimers involve such units.…”

Section: Introductionmentioning

confidence: 99%

Synthetically Induced 1→4‐C Branching Motif ‐ An Access Towards Dense Urethane Connecting Dendritic Scaffolds and Application in Nuclear Track Detection

Shetgaonkar

Nadkarni

2019

ChemistrySelect

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A series of dumbbell‐shaped urethane connecting polyoleifinic dendrimers, are synthesized from commercial AB2 monomer through the concept of post‐generative synthetic induction of novel 1→4‐C branching motif in divergent and convergent growth methodology using carbamoyl chloride reactivity. A synthetic protocol is conducted through the iterative process of O‐carbamoyl‐allylation of hydroxyls followed by Upjohn dihydroxylation of the allylic double bonds, leading to protection/deprotection free divergent pathway. In parallel, convergent growth route gains dendrimers in relatively good yields. Also, the process of O‐carbonyloxy‐allylation of [G‐1] polyol affords urethane‐carbonate framework providing access to 1→2‐C branching further. Incorporation of current branching motif results in dendritic scaffold with dense periphery at lower generations itself. Free radical cast polymerization of [G‐0.5] dendrimer with allyl diglycol carbonate (ADC) produces thermoset polymer films, showing good sensitivity and ability to permanently record nuclear tracks.

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Covalent and noncovalent films made up of sulfonimide-based dendrimers

Bondareva

Luchkin

Dagesyan

et al. 2021

Applied Surface Science

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Synthesis of sulfonimide-based dendrimers and dendrons possessing mixed 1 → 2 and 1 → 4 branching motifs

Cited by 5 publications

References 12 publications

Nanomaterials Interaction with Cell Membranes: Computer Simulation Studies

Nanomaterials Interaction with Cell Membranes: Computer Simulation Studies

Synthetically Induced 1→4‐C Branching Motif ‐ An Access Towards Dense Urethane Connecting Dendritic Scaffolds and Application in Nuclear Track Detection

Covalent and noncovalent films made up of sulfonimide-based dendrimers

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Synthesis of sulfonimide-based dendrimers and dendrons possessing mixed 1 → 2 and 1 → 4 branching motifs

Cited by 5 publications

References 12 publications

Nanomaterials Interaction with Cell Membranes: Computer Simulation Studies

Nanomaterials Interaction with Cell Membranes: Computer Simulation Studies

Synthetically Induced 1→4‐C Branching Motif ‐ An Access Towards Dense Urethane Connecting Dendritic Scaffolds and Application in Nuclear Track Detection

Covalent and noncovalent films made up of sulfonimide-based dendrimers

Contact Info

Product

Resources

About

Synthesis of sulfonimide-based dendrimers and dendrons possessing mixed 1 → 2 and 1 → 4 branching motifs