Synthesis of thieno[2,3-c]pyridine derived GRK2 inhibitors

New Hydrolyzable Tannin with Potent Antioxidant and α-Glucosidase Inhibitory Activity from Black Tea Produced from Camellia taliensis

“…The EtOAc extract was further isolated by various CC on Diaion HP20SS, RP-18, Toyopearl HW-40F, MCI-gel CHP20P, and Sephadex LH-20, to yield 32 compounds, including one undescribed hydrolyzable tannin (1) and one new natural product (24). The compounds, which had were in advance, were recognized as seven hydrolyzable tannins ( 2 (10) [29], quercetin 3-O-β-D-glucopyranoside (11) [30], kaempferol 3-O-rutinoside (12) [23], rutin (13) [31], kaempferol 3-O-β-D-galactopyranoside ( 14) [32], kaempferol 3-O-α-L-rhamnopyranoside (15) [33], quercetin ( 16) [34], quercetin 3-(2 -β-Dglucosyl)-α-L-rhamnopyranoside (17) [35], and kaempferol 3-(2 -β-D-glucosyl)-α-L-rhamnopy ranoside (18) [35], and 14 simple phenolics (19−32) including gallic acid (19) [36], 3,4dihydroxybenzoic acid (20) [37], p-hydroxybenzoic acid ( 21) [38], m-hydroxybenzoic acid (22) [39], methyl gallate ( 23) [40], 3-(2-methoxy-2-oxoethyl) benzoic acid (24) [41], chlorogenic acid (25) [42], 5-O-(E)-p-coumaroylquinic acid (26) [43], 5-O-caffeoylshikimic acid (27) [44], caffeic acid (28) [45], E-p-hydroxycinnamic acid (29) [46], 1-(3 ,4 -dihydroxycinnamoyl) cyclopenta ne-2,3-diol (30) [47], 3,4,8,9,10-pentahydroxydibenzo[b,d]pyran-6-one (31) [48], and (3R)...…”