Synthesis of Tween-Coated Silver Nanoparticles by a Plasma-Chemical Method: Catalytic and Antimicrobial

Скіба, Маргарита; Vorobyova, Viktoria; Коваленко, И. В.; Shakun, Anastasiia

doi:10.23939/chcht14.03.297

Cited by 10 publications

(4 citation statements)

References 24 publications

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“…Skiba et al investigated Tween 80 coated AgNP and produced stable colloids with a Tween 80 concentration of 2 µM in water. [63] Considering the high salt concentrations in our study, a higher required Tween 80 concentration is plausible. As for the mPEG-SH ligand, the used Tween 80 concentrations are clinically relevant.…”

Section: Colloidal Stabilitymentioning

confidence: 78%

Synergetic enhancing effects between platinum nano-sensitizers and clinically approved stabilizing ligands in proton therapy, causing high-yield double-strand breaks of plasmid DNA at relevant dose

Zwiehoff,

Hensel,

Rishmawi

et al. 2024

Preprint

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Proton therapy is used to eradicate tumors in sensitive areas by targeted delivery of energy. Its effectiveness can be amplified using nanoparticles as sensitizers, due to the production of reactive oxygen species (ROS) at the nanoparticle´s catalytically active surface, causing the cleavage of DNA. However, the impact of stabilizing macromolecular ligands capping the particles, needed for nanosensitizer dispersion in physiological fluids, is underexplored. In this work, we use initially ligand-free colloidal platinum nanoparticles (PtNP) fabricated by scalable laser synthesis in liquids, which allows studying particle and ligand effects separately. PtNP are incubated with stabilizing concentrations of the clinically approved ligands albumin, Tween, and polyethylene glycol, and irradiated with proton beams at clinically relevant doses (2 Gy and 5 Gy). At these doses, plasmid DNA cleavage larger than 55% of clustered DNA damage is achieved. BSA, Tween, and polyethylene glycol on the NP surface work as double strand breaking (DSB) enhancers and synergetic effects occur even at low and clinically relevant particle concentrations and irradiation doses. Here, DSB enhancement by ligand-capped PtNP even exceeds the sum of the individual ligand and particle effects. The presented fundamental correlations provide selection rules for nanosensitizer design in proton therapy.

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Section: Colloidal Stabilitymentioning

confidence: 78%

Synergetic enhancing effects between platinum nano-sensitizers and clinically approved stabilizing ligands in proton therapy, causing high-yield double-strand breaks of plasmid DNA at relevant dose

Zwiehoff,

Hensel,

Rishmawi

et al. 2024

Preprint

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show abstract

“…Silver nanoparticles (AgNPs)-alginate composite beads with different PVP concentration were synthesized as materials for water purification. Then Skiba and coworkers 16 have obtained Ag nanoparticles by a simple and eco-friendly atmospheric pressure plasma method, also using a capping agent. Effects of that agent concentration on the formation efficiency of the Ag nanoparticles, their average size and stability have been studied.…”

Section: Resultsmentioning

confidence: 99%

Telechelic Oligo(N-Vinylpyrolydone)swith Cumene Based Terminal Groups for Block-Copolymer and Nanoparticle Obtaining

Volianiuk¹,

Mitina²,

Kinash³

et al. 2022

ChChT

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“…10 Several forms for the preparation of metal nanoparticle films on solid substrates were already reported, such as sol-gel deposition of metal ions followed by thermal treatment, 11 vapor-deposition methods, 12 and also, the deposition of metal nanoparticles from colloidal dispersions. [13][14][15][16][17][18] Fig. 1.…”

Section: Introductionmentioning

confidence: 99%

Characterization, Antioxidant Activity, and In Silico Molecular Docking of Chitosan from Snail Shell Waste by Ultrasonic Technique

Umarudin¹,

Rahayu²,

Widyarti³

et al. 2023

ChChT

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Snails are often found in Indonesia, especially at Kediri, but the snail shell has no commercial value. This research report describes the characterization and antioxidant activity of chitosan from snail shell waste (chitosan-SSW) by ultrasonic technique and analyzes the potential of chitosan as an inhibitor of receptors of free radicals using an in silico molecular docking method. Characterization of chitosan-SSW was performed to analyze the content of water, protein, and functional groups as well as molecular weight, particle size, mor-phology, antioxidant activity, and in silico molecular docking. We found that chitosan-SSW with ultrasonic treatment had a high degree of deacetylation (DD) and high molecular weight (MW). The characteristic of chitosan-SSW was found to be as follows: water content of 0.43 %, protein content of 1.59 %, molecular weight of 2.198 kDa, and deacetylation degree value of 79.50 %. Importantly, chitosan-SSW had high antioxidant activity to potentially reduce free radical of DPPH with IC50 value of 2.44 µg/mL. Chitosan is predicted to have the potential as an inhibitor of lipoxygenase, CYP2C9, and NADPH-oxidase.

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Synthesis of Tween-Coated Silver Nanoparticles by a Plasma-Chemical Method: Catalytic and Antimicrobial

Cited by 10 publications

References 24 publications

Synergetic enhancing effects between platinum nano-sensitizers and clinically approved stabilizing ligands in proton therapy, causing high-yield double-strand breaks of plasmid DNA at relevant dose

Synergetic enhancing effects between platinum nano-sensitizers and clinically approved stabilizing ligands in proton therapy, causing high-yield double-strand breaks of plasmid DNA at relevant dose

Telechelic Oligo(N-Vinylpyrolydone)swith Cumene Based Terminal Groups for Block-Copolymer and Nanoparticle Obtaining

Characterization, Antioxidant Activity, and In Silico Molecular Docking of Chitosan from Snail Shell Waste by Ultrasonic Technique

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