Synthesis, Physicochemical Studies and Biological Applicationsof Oxovanadium(iv) Complexes With Schiff Bases Derived From 3-Phenyl-4-Amino-5-Mercapto-1, 2, 4-Triazoles and Benzil

Abstract

A series of some mononuclear oxovanadium(IV) complexes have been synthesized by the reactions of oxovanadium(IV) sulfate with Schiff base ligands derived from 3-(phenyl / substituted phenyl)-4-amino-5-mercapto-1, 2, 4-triazoles of aromatic carboxylic acids and benzyl. The complexes were analyzed by different spectroscopic methods (FTIR, UV-Vis., EPR), X-ray diffraction (XRD) analysis, elemental analysis, conductivity measurement, and cyclic voltammetry (CV) analysis. The non-electrolytic nature of the complexes was determined on the basis of the molar conductance values. The powder X-ray diffraction pattern has also been used to determine crystal size and type. On the basis of the physicochemical data, the tentative square- pyramidal geometry of the complexes has been proposed. In vitro antibacterial andantidiabeticproperties by alpha amylase inhibition activities of the selected complexes have also been determined.

Chemical Synthesis, Characterization, and Computational Investigation of Two Schiff Bases Derived From 3-(2-Hydroxyphenyl)-4-amino-4H-1,2,4-triazole-5- thiol and Their Corresponding Oxovanadium(IV) Complexes

“…The g-values and the spectra are typical of the data reported for square pyramidal oxovanadium(IV) complexes with an unpaired d-electron [15]. The EPR data justifies the structure and geometry of the synthesized oxovanadium(IV) complexes due to its close agreement with the structural identity revealed from other spectral and computational results [11,26]. The structural models of the Schiff base ligands and their oxovanadium(IV) complexes are proposed as shown in Fig.…”

“…This results in that the hyperfine splitting of the spectral line not being resolved properly in the complexes. This is due to higher nuclear moment and spin causing a broadening because of the longer relaxation time [11]. The X-band EPR spectra of oxovanadium(IV) complexes recorded at room temperature display a typical eight-line pattern of vanadium as shown in Fig.…”