Synthesis, physicochemical studies, embryos toxicity and DNA interaction of some new Iron(II) Schiff base amino acid complexes

Abdel‐Rahman, Laila H.; El‐Khatib, Rafat M.; Nassr, Lobna A. E.; Abu‐Dief, Ahmed M.

doi:10.1016/j.molstruc.2013.02.023

Cited by 128 publications

(89 citation statements)

References 52 publications

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“…The absorbance of each complex was measured at different pH values. pH values were adjusted using a series of Britton universal buffer [18][19][20]. TEM images were recorded using a JEM-2100 microscope.…”

Section: Physical Measurementsmentioning

confidence: 99%

Some New Nano-sized Mononuclear Cu(II) Schiff Base Complexes: Design, Characterization, Molecular Modeling and Catalytic Potentials in Benzyl Alcohol Oxidation

et al. 2016

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In the present contribution, some novel Cu(II) complexes were synthesized from tri-and tetradentate imine ligands. All the prepared compounds were elucidated by different physicochemical methods. Density Functional Theory calculations were carried out to explain the equilibrium geometry of the bsisnph and npisnph ligands and their Cu(II) complexes. Interaction of the synthesized ligands with Cu(II) affords nano-sized particles via TEM. The catalytic potentials of the prepared complexes has been tested within the oxidation of benzyl alcohol using an environmental friendly terminal oxidant, i.e. H 2 O 2 . The effect of various parameters, e.g. solvents, temperature and amount of catalyst was investigated. A mechanistic pathway of the catalytic oxidation was tentatively described and discussed. Graphical AbstractKeywords Cu(II) Schiff base complexes · TEM · Benzyl alcohol · Density Functional Theory · Catalytic activity · Hydrogen peroxide

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Section: Physical Measurementsmentioning

confidence: 99%

Some New Nano-sized Mononuclear Cu(II) Schiff Base Complexes: Design, Characterization, Molecular Modeling and Catalytic Potentials in Benzyl Alcohol Oxidation

et al. 2016

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“…Overtone's concept [42] and Tweedy's chelation theory [43], revealed that such increased activity results of the complexes have explained clearly by the researchers using the different micro-organisms. The lipid membrane that surrounds the cell positive discrimination route only the lipid-soluble resources due to which liposolubility is a significant factor, which controls the anti-fungal activity results by overtone's theory of cell permeability.…”

Section: Dna-absorption Spectral Titrationmentioning

confidence: 95%

Biological Screening Studies of DNA Relate Metal Complexes from Benzylidene-4-imino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one and 2-aminothiazole

Palanimurugan¹,

Kulandaisamy²

2018

Asian J. Chem.

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Novel terdentate cationic complexes of Cu(II), Ni(II), Co(II), Mn(II) and Zn(II) ion have been prepared using a Schiff base derived from benzylidene-4-imino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one and 2-aminothiazole. The structural features of metal-chelates have been confirmed by micro-analytical data, FAB-Mass spectra, powder XRD, SEM, FTIR, UV-visible, 1 H NMR, EPR, CV and thermal analysis techniques. The analytical data of the complexes correspond well with the general formula [ML2]Cl2. The high conductance data of metal chelates supports their 1:2 electrolytic nature. The magnetic susceptibility and electronic absorption spectra of the complexes indicate that all the metal-chelates exhibit octahedral geometry around the central metal ion. Powder XRD data and SEM images persist that the complexes are nano size grain with polycrystalline structure. DNA interaction studies of [CuL2]Cl2 complex have been done by electronic spectral and cyclic voltammetric measurements which revealed that the binding occurs through intercalation between complex and DNA interaction of [CuL2]Cl2 complex with CT-DNA leads to hypochromism. The MIC values against the growth of microorganisms are lower for metal chelates than the ligand. This is mainly due to lipophilicity of metal ion in complexes.

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“…450 cm -1 , which is assigned to ν(M-N) for this nitrogen [17]. A second band assignable to ν(C=N) is expected in the spectra of those complexes having anionic thiosemicarbazone ligands, since the anionic ligand formally has a double bond between N(2) and C(3) of the thiosemicarbazone moiety [18].…”

Section: Infrared Spectramentioning

confidence: 99%

Synthesis, Magnetic, Spectral and Biological Studies of Copper(II) Complexes of 4-Benzoyl-3-Methyl-1-Phenyl-2-Pyrazolin-5-One N(4)-Substituted Thiosemicarbazones

El‐Sawaf¹,

Nassar²,

El-Samanody³

2014

SJC

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Abstract:The synthesis and characterization of copper(II) complexes with 4-benzoyl-3-methyl-1-phenyl-2-pyrazolin-5-one thiosemicarbazone and N(4)-substituted thiosemicarbazones are reported. Elemental analysis, molar conductivities, magnetic measurements and spectral (i.r., electronic, e.s.r., and n.m.r.) studies have been used to characterize the complexes. The i.r. spectra show that the thiosemicarbazones behave as bidentate ligands, either in the thione or thiolato form. Stereochemistries are proposed for the complexes on the basis of spectral and magnetic studies. Both the thiosemicarbazones and their complexes show either modest or no growth inhibitory activity against Aspergillus niger and Paecilomyces variotii.

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Synthesis, physicochemical studies, embryos toxicity and DNA interaction of some new Iron(II) Schiff base amino acid complexes

Cited by 128 publications

References 52 publications

Some New Nano-sized Mononuclear Cu(II) Schiff Base Complexes: Design, Characterization, Molecular Modeling and Catalytic Potentials in Benzyl Alcohol Oxidation

Some New Nano-sized Mononuclear Cu(II) Schiff Base Complexes: Design, Characterization, Molecular Modeling and Catalytic Potentials in Benzyl Alcohol Oxidation

Biological Screening Studies of DNA Relate Metal Complexes from Benzylidene-4-imino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one and 2-aminothiazole

Synthesis, Magnetic, Spectral and Biological Studies of Copper(II) Complexes of 4-Benzoyl-3-Methyl-1-Phenyl-2-Pyrazolin-5-One N(4)-Substituted Thiosemicarbazones

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