Synthesis, spectral analysis and anti-bacterial study of N -substituted derivatives of 2-(5-(1-(phenylsulfonyl)piperidin-4-yl)-1,3,4-oxadiazol-2-ylthio)acetamide

Synthesis and Evaluation of some New 5-Substituted-1,3,4- oxadiazol-2yl-4-(morpholin-4yl Sulfonyl)benzyl Sulfides as Antibacterial Agent

“…Synthesized compounds were screened against four Gram-negative and two Gram-positive bacteria as previously reported [13][14][15]. Briefly, the test organisms were maintained on stock culture agar medium.…”

“…This current work (an extension of previous work, [13][14][15]) aimed to synthesize poly-functional compounds having 1,3,4-oxadiaozloe and sulfa morpholine moiety together in an individual molecule. It was expected that 2,5-disubstituted 1,3,4-oxadiazole ring along with the potential morpholine moiety will boost up the antibacterial activity of the molecule and hence the synthesized compounds were screened against clinically isolated bacteria.…”

Synthesis of N-substituted acetamide derivatives of azinane-bearing 1,3,4-oxadiazole nucleus and screening for antibacterial activity

“…The derivatives of heterocyclic compounds have been found to be bioactive, including naturally occurring and synthetically prepared ones [2]. Among these compounds, 1,3,4-oxadiazole derivatives have been synthesized and evaluated for a number of biological activities including antidepressant, anticonvulsant, anticancer, antimicrobial, etc., during the last two decades [2][3][4][5][6][7][8][9][10][11]. Another bioactive heterocyclic moiety, piperidine or azinane, is found to be a part of many natural and synthetic bioactive compounds [12].…”

Synthesis of N'-Substituted-2-(5-(4-Chlorophenyl)-1,3,4- oxadiazol-2-ylthio)acetohydrazide Derivatives as Suitable Antibacterial Agents

“…Heterocyclic compounds have often been synthesized because of their broad spectrum of biological activities [2]. The 2,5-substituted-1,3,4-oxadiazole derivatives, which have often been synthesized in the last decade, exhibit a number of biological activities [3][4][5][6][7] . In continuation of a previous synthetic work using 1,3,4-oxadiazole derivatives [8,9], N-substituted derivatives of 2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-ylthio)acetohydrazide have been synthesized in this study to determine their antibacterial potential.…”