Synthesis, spectral characterization and crystal structure of a novel trinuclear di-n-butyltin(IV) complex with pyruvic acid-N(4)-cyclohexylthiosemicarbazone (H2PACT)

Abstract

a b s t r a c tA new trinuclear di-n-butyltin(IV) complex with pyruvic acid-N(4)-cyclohexylthiosemicarbazone (H 2 PACT) ligand was synthesized and characterized by elemental analyses, molar conductivity, UVeVis, FT-IR, 1 H, 119 Sn NMR spectroscopy and single crystal X-ray study. Single crystal X-ray diffraction data revealed that this complex was trinuclear cyclic fashion with the pyruvic acid-N(4)-cyclohexylthiosemicarbazone ligand. In the trinuclear di-n-butyltin(IV) complex, the ligand (H 2 PACT) is coordinated to the central tin(IV) atoms via the carboxylato-O, the azomethine-N and the thiolato-S atoms. The trinuclear tin system is formed by the bridges through the carbonyl oxygen atom of the carboxylate moieties and making the tin atom of seven coordinated in distorted pentagonal bipyramidal geometry. Single crystal X-ray data indicates that the complex (1) crystallized in cubic system with spaceand final R 1 ¼ 0.0390, wR 2 ¼ 0.0843 for observed reflections 4582(I > 2s(I)).

Synthesis, Characterization, and Antibacterial Activities of Organotin(IV) Complexes with 2‐Acetylpyridine‐N(4)‐cyclohexylthiosemicarbazone (HAPCT)

“…The azomethine proton (CH 3 CN) signal appears at 2.37 ppm in the free ligand ( 1 ), which is shifted to downfield at 2.73–2.45 ppm in the complexes ( 2–6 ). This downfield shift indicating the azomethine nitrogen atom is coordinated to the Sn(IV) atom . The proton resonance signals for N4‐H and CyC1‐H are appeared at 10.31–10.27 and 8.11–7.25 ppm in the complexes ( 2–6 ).…”

Schiff base‐nickel, palladium, and platinum complexes derived from N‐cyclohexyl hydrazine carbothioamide and 3‐hydroxy‐4‐methoxybenzaldehyde: Selective antiproliferative and proapoptotic effects against colorectal carcinoma

“…The chemicals, 3‐hydroxy‐4‐methoxy‐benzaldehyde, Ni(OAc) 2 ·4H 2 O, Pd(OAc) 2 , and K 2 PtCl 4 were purchased from Sigma Chemical Co. All organic solvents used were purified according to the prescribed procedure (Haque, Salam, & Arafath, ; Salam, Affan, Ahmad, Jusoh, et al, ). Human colorectal carcinoma (HCT‐116), human cervical cancer (Hela) cell line, melanoma (B16F10) cells, and human endothelial normal cell line (Ea.hy 926) were purchased from ATCC.…”