Synthesis, spectral characterization, cyclic voltammety, molecular modeling and catalytic activity of sulfa-drug divalent metal complexes

Abstract

Complexes of cobalt(II), nickel(II), copper(II), zinc(II) and Hafnium(II) of general composition [M(L)2(Cl)2] have been synthesized [L = 4-(phenylphosphinylideneamino-N-thiazolylbenzenesulfonamide]. The elemental analysis, molar conductance measurements, magnetic susceptibility measurements, mass, IR, UV, NMR, SEM, EDX, thermal and EPR spectral studies of the compounds led to the conclusion that the ligand acts as a bidentate manner. The molar conductance of the complexes in fresh solution of DMSO lies in the range of 7.46–9.13 Ω-1 cm2mol‒1 indicating their non-electrolytic behavior. On the basis of analytical and spectroscopic techniques, octahedral geometry of the complexes was proposed. The ligand acts as bidentate ligand, coordinated through sulfonamide oxygen and thiazole nitrogen atoms. The ligand field parameters were calculated for Co(II), Ni(II) and Cu(II) complexes and their values were found in the range reported for a octahedral structure. The catalytic activities of the divalent metal complexes have been studied in the oxidation of cyclohexane, using environmental friendly oxidant, hydrogen peroxide. Complex with rough surface has shown higher catalytic activity compared to the other complexes. The molecular parameters of the ligand and its Co(II) and Hf(II) complexes have been calculated.

Synthesis, Characterization, Fluorescence, Electrochemical, Antimicrobial and Cytotoxic studies of Cobalt(II), Nickel(II) and Copper(II) Complexes with N-4-Methylphenyl (2,4-dihydroxyacetophenylideneimine)

“…The reduction peak is viewed at EP c = -0.994V and the oxidation peak is noted at EP a = 0.730V. This couple is quasi-reversible and ratio between oxidation and reduction current suggests the process to be simple one-electron transfer 31 . The voltammogram of [Cu(NMPDHAPI) 2 ] displays one oxidation peak at EP a = -0.715V and the corresponding reduction peak at EP c = -1.224V.…”