Synthesis, Spectroscopic, and Antimicrobial Studies on Bivalent Zinc and Mercury Complexes of 2‐Formylpyridine Thiosemicarbazone

Abstract

A series of metal complexes of Zn(II) and Hg(II) having the general composition [M(L)2]X2 [where L = 2-formylpyridine thiosemicarbazone; M = Zn(II) and Hg(II); X = Cl−, NO3 − and 1/2SO4 2−] have been prepared and characterized by elemental chemical analysis, molar conductance, and spectral (IR and mass) studies. The IR spectral data suggests the involvement of sulphur and azomethane nitrogen in coordination to the central metal ion. On the basis of spectral studies, a tetrahedral geometry has been assigned for Zn(II) and Hg(II) complexes. The free ligand and its metal complexes have been tested in vitro against a number of microorganisms in order to assess their antimicrobial properties.

Synthesis, Characterization, and Biological Evaluation of Some 3d-Metal Complexes of Schiff Base Derived from Xipamide Drug

“…The base peak at / 117 may be due to the zinc metal linked to the donor atoms of the ligand. Such type of fragmentation pattern has been reported by many workers [31,32].…”

Antibacterial Activity of 2-[(2-Chloro-4-Methylbenzylidene) Amino] Pyridin-4-Ol and Its Some Transitional Metal Ion Complexes

“…These peaks support to the structure of the complexes. The different molecular ion peaks appeared in the mass spectra of complexes are attributed to the fragmentation of the metal complex molecule obtained from the rupture of different bonds inside the molecule [26] by successive degradation leading to many more important peaks due to formation of various radicals [27]. The spectra of complexes show molecular ion peaks in good agreement with the structure suggested by elemental analysis, spectral and magnetic studies.…”

Synthesis, Molecular Modeling, and Biological Activity of Zinc(II) Salts with 1,4‐Bis(benzimidazol‐2‐yl)benzene

“…e zinc(II) is responsible for the function of carboxy peptidase A and carbonic anhydrase in biological systems [7][8][9]. Further, a number of Zn(II) complexes with variety of ligand show antimicrobial, anticarcinogenic, veterinary, anthelmintic, and poliovirus inhibitor activities [10][11][12][13]. us, the coordination behaviour of benzimidazoles with zinc is of considerable importance.…”