Synthesis, Spectroscopic Characterization and Antibacterial Activity of Organotin(IV) Complexes Containing Hydrazone Ligand: X-ray Single Crystal Structure of [<i>n</i>-Bu₂Sn(H₂PAI).H₂O]

Abstract

Five new organotin(IV) complexes with pyruvic acid isonicotinoyl hydrazone [H 4 PAI (1

Synthesis, characterization and antimicrobial activities of organotin(IV) complexes with ethylthioglycolate

“…The biological importance of organotins has been supported by studies concentrating on structureactivity correlations that deal mainly with structural aspects and antitumour activity, and also linked with possible tumorigenic activity (Shahid et al, 2006). This aspect has been attracting the attention of a number of researchers and a multitude of structural types have been discovered (Affan et al, 2009). These compounds have been generally used as agrochemicals (David, et al, 2008) and antifouling paints (Smith et al, 1979) due to their low phytotoxicity and favourable environmental degradation to non-toxic inorganic residues.…”

Synthesis, characterization, crystal structure and theoretical approach of (E)-2-[(3-carboxylphenylimino)methylene]phenoxyacetic acid

“…Schiff bases and aromatic carboxyl derivatives had been extensively investigated in the past decades, because they own properties of strong metals chelateing tendency, plant growth regulating activity, photochemistry and their vital role in photopolymerization activity [1][2][3][4][5][6][7]. Many of these compounds possess biochemical and pharmacological properties, especially their antimicrobial, anti-tumor and anti-inflammatory activity, which may afford them potential as therapeutic agents and make them very useful [8,9].…”

Ligational behavior of new mononucleating NOO ethyl pyruvate Schiff base towards 3d metal(II) ions: an emphasis on antiproliferative and photocleavage property

“…[16] On the other hand, transition metal compounds of ethyl pyruvate Schiff base have been tested for their in vitro activity against a large variety of tumor cell lines and have been found to be as effective as traditional heavy metal anticancer drugs such as cisplatin. [17,18] In addition to the aforesaid applications, these compounds are also of interest in view of the considerable structural diversity they possess. Hence it was thought worth considering that the metal complexes formed by the combination of transition metal ion with a potent hydrazone Schiff base ligand should be more biologically active than the metal salts or the ligand individually.…”