Synthetic approaches to thiathromboxanes. Part 2. Synthesis of structural isomers of thiathromboxane A2

McDonald, Brian P.; Steele, R.; Sutherland, J. K.; Leslie, Bruce W.; Brewster, Andrew G.

doi:10.1039/p19880000675

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1988

2022

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Cited by 17 publications

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“…14 Thiopyrans are used as key units in medicinal chemistry and as versatile building blocks in organic synthesis. 15 For example, it has been reported that thiopyrans were widely used in the construction of analogues of natural products with various biological activities, such as tetrahydrodicranenone, 16 serricornin, 17 thromoboxanes, 18 and cyclopentanoids. 19 As a result, a great deal of efforts has been drawn to develop new and efficient synthetic routes to thiopyrans.…”

Section: Introductionmentioning

confidence: 99%

Novel one-pot Facile Synthesis of Thiopyranopyrazole Using [H mim]HSO4 Catalyst

Srivastava¹,

Singh²,

Singh³

2014

Croat. Chem. Acta

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An efficient and easy protocol has been developed for synthesis of thiopyranopyrazole by using [H mim]HSO 4 as recyclable catalyst under solvent-free condition at room temperature. This environmentally benign method has advantages, such as high yield of products, simple work-up procedure, and avoidance of the organic solvents, which will contribute in serving as a green process greatly. The catalyst was easily recovered and reused without any considerable loss of activity.

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