Synthetic Hybrid Biosensors

Shanker, Apoorv; Lee, Kangwon; Kim, Dong Ha

doi:10.1002/3527600906.mcb.20130069

Cited by 5 publications

(5 citation statements)

References 148 publications

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“…(a) Potentiometric biosensors: Potentiometric biosensors measure the charge accumulated due to the analyte and bioreceptor interaction at the working electrode relative to the reference electrode under zero current. To transform a biochemical reaction into a potential signal, ion-selective electrodes and ion-sensitive field-effect transistors are used [74][75][76][77][78]. (b) Amperometric biosensors: Amperometric biosensors operate in a two or threeelectrode configurations.…”

Section: Electrochemical Biosensorsmentioning

confidence: 99%

“…In this biosensor, an electrochemical reaction occurs on the transducer surface between bioreceptor and analyte producing detectable electrochemical signals in terms of voltage, current, impedance, and capacitance [ 74 , 75 ]. Based on the transduction principle, electrochemical biosensors are categorized as: (a) Potentiometric, (b) amperometric, (c) impedimetric, (d) conductometric, and (e) voltammetric [ 74 , 75 , 76 , 77 ]. Figure 6 illustrates the schematic diagrams of (a) amperometric/voltammetric, (b) potentiometric, (c) conductometric, and (d) impedimetric (showing the equivalent circuit) biosensors.…”

Section: Biosensormentioning

confidence: 99%

“…These sensors measure the current produced due to electrochemical oxidation or reduction of electroactive species at the working electrode when a constant potential is applied to the working electrode with respect to the reference electrode. The current produced on the surface of the working electrode is proportional to the concentration of the analyte present in the solution [ 74 , 75 , 76 , 77 ]. Compared with potentiometric biosensors, this method allows sensitive, fast, precise, and linear response, which makes it more suitable for mass production.…”

Section: Biosensormentioning

confidence: 99%

See 2 more Smart Citations

A Review on Biosensors and Recent Development of Nanostructured Materials-Enabled Biosensors

Naresh

Lee

2021

Sensors

1,076

427

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A biosensor is an integrated receptor-transducer device, which can convert a biological response into an electrical signal. The design and development of biosensors have taken a center stage for researchers or scientists in the recent decade owing to the wide range of biosensor applications, such as health care and disease diagnosis, environmental monitoring, water and food quality monitoring, and drug delivery. The main challenges involved in the biosensor progress are (i) the efficient capturing of biorecognition signals and the transformation of these signals into electrochemical, electrical, optical, gravimetric, or acoustic signals (transduction process), (ii) enhancing transducer performance i.e., increasing sensitivity, shorter response time, reproducibility, and low detection limits even to detect individual molecules, and (iii) miniaturization of the biosensing devices using micro-and nano-fabrication technologies. Those challenges can be met through the integration of sensing technology with nanomaterials, which range from zero- to three-dimensional, possessing a high surface-to-volume ratio, good conductivities, shock-bearing abilities, and color tunability. Nanomaterials (NMs) employed in the fabrication and nanobiosensors include nanoparticles (NPs) (high stability and high carrier capacity), nanowires (NWs) and nanorods (NRs) (capable of high detection sensitivity), carbon nanotubes (CNTs) (large surface area, high electrical and thermal conductivity), and quantum dots (QDs) (color tunability). Furthermore, these nanomaterials can themselves act as transduction elements. This review summarizes the evolution of biosensors, the types of biosensors based on their receptors, transducers, and modern approaches employed in biosensors using nanomaterials such as NPs (e.g., noble metal NPs and metal oxide NPs), NWs, NRs, CNTs, QDs, and dendrimers and their recent advancement in biosensing technology with the expansion of nanotechnology.

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Section: Electrochemical Biosensorsmentioning

confidence: 99%

Section: Biosensormentioning

confidence: 99%

Section: Biosensormentioning

confidence: 99%

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A Review on Biosensors and Recent Development of Nanostructured Materials-Enabled Biosensors

Naresh

Lee

2021

Sensors

1,076

427

View full text Add to dashboard Cite

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“…This current can be correlated with the concentration of the electroactive species present at which it is generated. Identifying electrical attributes (like resistance, current, potential, capacitance, and impedance), 151–154 which are discerned and quantified through diverse methods such as potentiometric, conductometric, amperometric, or voltametric 155,156 having high sensitivity and selectivity. Fig.…”

Section: Development Of Nanomaterial-based Sensing Techniquesmentioning

confidence: 99%

Current advancement in nanomaterial-based emerging techniques for the determination of aminoglycosides antibiotics for antibiotic resistance surveillances

Sajwan,

Hashmi,

Himanshu

et al. 2024

Mater. Adv.

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“…The reference electrode, usually positioned at a distance from the reaction site, serves to maintain a known stable potential [ 166 ]. As the reaction takes place, the electrochemical reaction (redox potential changes) can be detected and measured in terms of current, voltage, impedance and capacitance [ 175 , 176 ]. Table 2 summarises the types of electrochemical biosensors based on their electrochemical transduction principle namely potentiometric, amperometric, impedimetric, and voltammetric biosensors.…”

Section: Biosensors Developed For Salmonella Detectionmentioning

confidence: 99%

Advancement in Salmonella Detection Methods: From Conventional to Electrochemical-Based Sensing Detection

et al. 2021

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Large-scale food-borne outbreaks caused by Salmonella are rarely seen nowadays, thanks to the advanced nature of the medical system. However, small, localised outbreaks in certain regions still exist and could possess a huge threat to the public health if eradication measure is not initiated. This review discusses the progress of Salmonella detection approaches covering their basic principles, characteristics, applications, and performances. Conventional Salmonella detection is usually performed using a culture-based method, which is time-consuming, labour intensive, and unsuitable for on-site testing and high-throughput analysis. To date, there are many detection methods with a unique detection system available for Salmonella detection utilising immunological-based techniques, molecular-based techniques, mass spectrometry, spectroscopy, optical phenotyping, and biosensor methods. The electrochemical biosensor has growing interest in Salmonella detection mainly due to its excellent sensitivity, rapidity, and portability. The use of a highly specific bioreceptor, such as aptamers, and the application of nanomaterials are contributing factors to these excellent characteristics. Furthermore, insight on the types of biorecognition elements, the principles of electrochemical transduction elements, and the miniaturisation potential of electrochemical biosensors are discussed.

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Synthetic Hybrid Biosensors

Cited by 5 publications

References 148 publications

A Review on Biosensors and Recent Development of Nanostructured Materials-Enabled Biosensors

A Review on Biosensors and Recent Development of Nanostructured Materials-Enabled Biosensors

Current advancement in nanomaterial-based emerging techniques for the determination of aminoglycosides antibiotics for antibiotic resistance surveillances

Advancement in Salmonella Detection Methods: From Conventional to Electrochemical-Based Sensing Detection

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